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Role of Sirtuin-1 in Neonatal Hypoxic-Ischemic Encephalopathy and Its Underlying Mechanism

BACKGROUND: Neonatal hypoxic-ischemic encephalopathy (HIE) is a dreaded disease and one of the leading causes of severe neurological dysfunction in neonates. The present study explored the functions of Sirtuin-1 (SIRT1) in neonatal HIE. MATERIAL/METHODS: A HIE neonatal rat model was generated to det...

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Detalles Bibliográficos
Autores principales: Zhang, Zhen, Chen, Xin, Liu, Sichen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461657/
https://www.ncbi.nlm.nih.gov/pubmed/32826847
http://dx.doi.org/10.12659/MSM.924544