In silico Design of Phl p 6 Variants With Altered Fold-Stability Significantly Impacts Antigen Processing, Immunogenicity and Immune Polarization

Introduction: Understanding, which factors determine the immunogenicity and immune polarizing properties of proteins, is an important prerequisite for designing better vaccines and immunotherapeutics. While extrinsic immune modulatory factors such as pathogen associated molecular patterns are well-u...

Descripción completa

Detalles Bibliográficos
Autores principales: Winter, Petra, Stubenvoll, Stefan, Scheiblhofer, Sandra, Joubert, Isabella A., Strasser, Lisa, Briganser, Carolin, Soh, Wai Tuck, Hofer, Florian, Kamenik, Anna Sophia, Dietrich, Valentin, Michelini, Sara, Laimer, Josef, Lackner, Peter, Horejs-Hoeck, Jutta, Tollinger, Martin, Liedl, Klaus R., Brandstetter, Johann, Huber, Christian G., Weiss, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461793/
https://www.ncbi.nlm.nih.gov/pubmed/33013833
http://dx.doi.org/10.3389/fimmu.2020.01824

Ejemplares similares

Ejemplares similares