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Melatonin Enhances the Therapeutic Effect of Plasma Exosomes Against Cerebral Ischemia-Induced Pyroptosis Through the TLR4/NF-κB Pathway
INTRODUCTION: Ischemic stroke-induced inflammation and inflammasome-dependent pyroptotic neural death cause serious neurological injury. Nano-sized plasma exosomes have exhibited therapeutic potential against ischemia and reperfusion injury by ameliorating inflammation. To enhance its therapeutic po...
Autores principales: | Wang, Kankai, Ru, Junnan, Zhang, Hengli, Chen, Jiayu, Lin, Xiao, Lin, Zhongxiao, Wen, Min, Huang, Lijie, Ni, Haoqi, Zhuge, Qichuan, Yang, Su |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461850/ https://www.ncbi.nlm.nih.gov/pubmed/33013286 http://dx.doi.org/10.3389/fnins.2020.00848 |
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