Commentary: Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model

Detalles Bibliográficos
Autores principales: Rai, Sachchida Nand, Chaturvedi, Vivek K., Singh, Brijesh Kumar, Singh, Mohan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461938/
https://www.ncbi.nlm.nih.gov/pubmed/32973484
http://dx.doi.org/10.3389/fnagi.2020.00219
_version_ 1783576824810307584
author Rai, Sachchida Nand
Chaturvedi, Vivek K.
Singh, Brijesh Kumar
Singh, Mohan P.
author_facet Rai, Sachchida Nand
Chaturvedi, Vivek K.
Singh, Brijesh Kumar
Singh, Mohan P.
author_sort Rai, Sachchida Nand
collection PubMed
description
format Online
Article
Text
id pubmed-7461938
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-74619382020-09-23 Commentary: Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model Rai, Sachchida Nand Chaturvedi, Vivek K. Singh, Brijesh Kumar Singh, Mohan P. Front Aging Neurosci Neuroscience Frontiers Media S.A. 2020-08-18 /pmc/articles/PMC7461938/ /pubmed/32973484 http://dx.doi.org/10.3389/fnagi.2020.00219 Text en Copyright © 2020 Rai, Chaturvedi, Singh and Singh. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Rai, Sachchida Nand
Chaturvedi, Vivek K.
Singh, Brijesh Kumar
Singh, Mohan P.
Commentary: Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model
title Commentary: Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model
title_full Commentary: Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model
title_fullStr Commentary: Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model
title_full_unstemmed Commentary: Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model
title_short Commentary: Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model
title_sort commentary: trem2 deletion reduces late-stage amyloid plaque accumulation, elevates the aβ42:aβ40 ratio, and exacerbates axonal dystrophy and dendritic spine loss in the ps2app alzheimer's mouse model
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461938/
https://www.ncbi.nlm.nih.gov/pubmed/32973484
http://dx.doi.org/10.3389/fnagi.2020.00219
work_keys_str_mv AT raisachchidanand commentarytrem2deletionreduceslatestageamyloidplaqueaccumulationelevatestheab42ab40ratioandexacerbatesaxonaldystrophyanddendriticspinelossintheps2appalzheimersmousemodel
AT chaturvedivivekk commentarytrem2deletionreduceslatestageamyloidplaqueaccumulationelevatestheab42ab40ratioandexacerbatesaxonaldystrophyanddendriticspinelossintheps2appalzheimersmousemodel
AT singhbrijeshkumar commentarytrem2deletionreduceslatestageamyloidplaqueaccumulationelevatestheab42ab40ratioandexacerbatesaxonaldystrophyanddendriticspinelossintheps2appalzheimersmousemodel
AT singhmohanp commentarytrem2deletionreduceslatestageamyloidplaqueaccumulationelevatestheab42ab40ratioandexacerbatesaxonaldystrophyanddendriticspinelossintheps2appalzheimersmousemodel

Ejemplares similares