Differential Roles of IDO1 and IDO2 in T and B Cell Inflammatory Immune Responses

Indoleamine-2,3-dioxygenase (IDO)1 and IDO2 are two closely related tryptophan catabolizing enzymes encoded by linked genes. The IDO pathway is also immunomodulatory, with IDO1 well-characterized as a mediator of tumor immune evasion. Due to its homology with IDO1, IDO2 has been proposed to have a s...

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Detalles Bibliográficos
Autores principales: Merlo, Lauren M. F., DuHadaway, James B., Montgomery, James D., Peng, Wei-Dan, Murray, Peter J., Prendergast, George C., Caton, Andrew J., Muller, Alexander J., Mandik-Nayak, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461966/
https://www.ncbi.nlm.nih.gov/pubmed/32973768
http://dx.doi.org/10.3389/fimmu.2020.01861

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461966/
https://www.ncbi.nlm.nih.gov/pubmed/32973768
http://dx.doi.org/10.3389/fimmu.2020.01861

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