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Protein Tyrosine Phosphatase Non-Receptor Type 2 Function in Dendritic Cells Is Crucial to Maintain Tissue Tolerance
Protein tyrosine phosphatase non-receptor type 2 (PTPN2) plays a pivotal role in immune homeostasis and has been associated with human autoimmune and chronic inflammatory diseases. Though PTPN2 is well-characterized in lymphocytes, little is known about its function in innate immune cells. Our findi...
Autores principales: | Hering, Larissa, Katkeviciute, Egle, Schwarzfischer, Marlene, Busenhart, Philipp, Gottier, Claudia, Mrdjen, Dunja, Komuczki, Juliana, Wawrzyniak, Marcin, Lang, Silvia, Atrott, Kirstin, Becher, Burkhard, Rogler, Gerhard, Scharl, Michael, Spalinger, Marianne R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462014/ https://www.ncbi.nlm.nih.gov/pubmed/32973765 http://dx.doi.org/10.3389/fimmu.2020.01856 |
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