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Information theoretic measures for quantifying sequence–ensemble relationships of intrinsically disordered proteins
Intrinsically disordered proteins (IDPs) contribute to a multitude of functions. De novo design of IDPs should open the door to modulating functions and phenotypes controlled by these systems. Recent design efforts have focused on compositional biases and specific sequence patterns as the design fea...
Autores principales: | Cohan, Megan C, Ruff, Kiersten M, Pappu, Rohit V |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462041/ https://www.ncbi.nlm.nih.gov/pubmed/31375817 http://dx.doi.org/10.1093/protein/gzz014 |
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