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miR760 regulates ATXN1 levels via interaction with its 5′ untranslated region
Identifying modifiers of dosage-sensitive genes involved in neurodegenerative disorders is imperative to discover novel genetic risk factors and potential therapeutic entry points. In this study, we focus on Ataxin-1 (ATXN1), a dosage-sensitive gene involved in the neurodegenerative disease spinocer...
Autores principales: | Nitschke, Larissa, Tewari, Ambika, Coffin, Stephanie L., Xhako, Eder, Pang, Kaifang, Gennarino, Vincenzo A., Johnson, Jennifer L., Blanco, Francisco A., Liu, Zhandong, Zoghbi, Huda Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462065/ https://www.ncbi.nlm.nih.gov/pubmed/32763910 http://dx.doi.org/10.1101/gad.339317.120 |
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