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miR760 regulates ATXN1 levels via interaction with its 5′ untranslated region

Identifying modifiers of dosage-sensitive genes involved in neurodegenerative disorders is imperative to discover novel genetic risk factors and potential therapeutic entry points. In this study, we focus on Ataxin-1 (ATXN1), a dosage-sensitive gene involved in the neurodegenerative disease spinocer...

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Detalles Bibliográficos
Autores principales:	Nitschke, Larissa, Tewari, Ambika, Coffin, Stephanie L., Xhako, Eder, Pang, Kaifang, Gennarino, Vincenzo A., Johnson, Jennifer L., Blanco, Francisco A., Liu, Zhandong, Zoghbi, Huda Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462065/ https://www.ncbi.nlm.nih.gov/pubmed/32763910 http://dx.doi.org/10.1101/gad.339317.120

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