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Age-group-targeted testing for COVID-19 as a new prevention strategy

Robust testing and tracing are key to fighting the menace of coronavirus disease 2019 (COVID-19). This outbreak has progressed with tremendous impact on human life, society and economy. In this paper, we propose an age-structured SIQR model to track the progression of the pandemic in India, Italy an...

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Autores principales: Upadhyay, Ranjit Kumar, Chatterjee, Sourin, Saha, Satvik, Azad, Rajeev K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462111/
https://www.ncbi.nlm.nih.gov/pubmed/32904917
http://dx.doi.org/10.1007/s11071-020-05879-x
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author Upadhyay, Ranjit Kumar
Chatterjee, Sourin
Saha, Satvik
Azad, Rajeev K.
author_facet Upadhyay, Ranjit Kumar
Chatterjee, Sourin
Saha, Satvik
Azad, Rajeev K.
author_sort Upadhyay, Ranjit Kumar
collection PubMed
description Robust testing and tracing are key to fighting the menace of coronavirus disease 2019 (COVID-19). This outbreak has progressed with tremendous impact on human life, society and economy. In this paper, we propose an age-structured SIQR model to track the progression of the pandemic in India, Italy and USA, taking into account the different age structures of these countries. We have made predictions about the disease dynamics, identified the most infected age groups and analysed the effectiveness of social distancing measures taken in the early stages of infection. The basic reproductive ratio [Formula: see text] has been numerically calculated for each country. We propose a strategy of age-targeted testing, with increased testing in the most proportionally infected age groups. We observe a marked flattening of the infection curve upon simulating increased testing in the 15–40 year age groups in India. Thus, we conclude that social distancing and widespread testing are effective methods of control, with emphasis on testing and identifying the hot spots of highly infected populations. It has also been suggested that a complete lockdown, followed by lockdowns in selected regions, is more effective than the reverse.
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spelling pubmed-74621112020-09-02 Age-group-targeted testing for COVID-19 as a new prevention strategy Upadhyay, Ranjit Kumar Chatterjee, Sourin Saha, Satvik Azad, Rajeev K. Nonlinear Dyn Original Paper Robust testing and tracing are key to fighting the menace of coronavirus disease 2019 (COVID-19). This outbreak has progressed with tremendous impact on human life, society and economy. In this paper, we propose an age-structured SIQR model to track the progression of the pandemic in India, Italy and USA, taking into account the different age structures of these countries. We have made predictions about the disease dynamics, identified the most infected age groups and analysed the effectiveness of social distancing measures taken in the early stages of infection. The basic reproductive ratio [Formula: see text] has been numerically calculated for each country. We propose a strategy of age-targeted testing, with increased testing in the most proportionally infected age groups. We observe a marked flattening of the infection curve upon simulating increased testing in the 15–40 year age groups in India. Thus, we conclude that social distancing and widespread testing are effective methods of control, with emphasis on testing and identifying the hot spots of highly infected populations. It has also been suggested that a complete lockdown, followed by lockdowns in selected regions, is more effective than the reverse. Springer Netherlands 2020-09-01 2020 /pmc/articles/PMC7462111/ /pubmed/32904917 http://dx.doi.org/10.1007/s11071-020-05879-x Text en © Springer Nature B.V. 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Original Paper
Upadhyay, Ranjit Kumar
Chatterjee, Sourin
Saha, Satvik
Azad, Rajeev K.
Age-group-targeted testing for COVID-19 as a new prevention strategy
title Age-group-targeted testing for COVID-19 as a new prevention strategy
title_full Age-group-targeted testing for COVID-19 as a new prevention strategy
title_fullStr Age-group-targeted testing for COVID-19 as a new prevention strategy
title_full_unstemmed Age-group-targeted testing for COVID-19 as a new prevention strategy
title_short Age-group-targeted testing for COVID-19 as a new prevention strategy
title_sort age-group-targeted testing for covid-19 as a new prevention strategy
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462111/
https://www.ncbi.nlm.nih.gov/pubmed/32904917
http://dx.doi.org/10.1007/s11071-020-05879-x
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