A MALT1 inhibitor suppresses human myeloid DC, effector T-cell and B-cell responses and retains Th1/regulatory T-cell homeostasis

The paracaspase mucosa-associated lymphoid tissue lymphoma translocation protein-1 (MALT1) regulates nuclear-factor-kappa-B (NF-κB) activation downstream of surface receptors with immunoreceptor tyrosine-based activation motifs (ITAMs), such as the B-cell or T-cell receptor and has thus emerged as a...

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Detalles Bibliográficos
Autores principales: Dumont, Celine, Sivars, Ulf, Andreasson, Theresa, Odqvist, Lina, Mattsson, Johan, DeMicco, Amy, Pardali, Katerina, Johansson, Gustav, Yrlid, Linda, Cox, Rhona J., Seeliger, Frank, Larsson, Marie, Gehrmann, Ulf, Davis, Andrew M., Vaarala, Outi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462277/
https://www.ncbi.nlm.nih.gov/pubmed/32870913
http://dx.doi.org/10.1371/journal.pone.0222548

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