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Transcriptional signatures in histologic structures within glioblastoma tumors may predict personalized drug sensitivity and survival
BACKGROUND: Glioblastoma is a rapidly fatal brain cancer that exhibits extensive intra- and intertumoral heterogeneity. Improving survival will require the development of personalized treatment strategies that can stratify tumors into subtypes that differ in therapeutic vulnerability and outcomes. G...
Autores principales: | Kersch, Cymon N, Claunch, Cheryl J, Ambady, Prakash, Bucher, Elmar, Schwartz, Daniel L, Barajas, Ramon F, Iliff, Jeffrey J, Risom, Tyler, Heiser, Laura, Muldoon, Leslie L, Korkola, James E, Gray, Joe W, Neuwelt, Edward A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462280/ https://www.ncbi.nlm.nih.gov/pubmed/32904984 http://dx.doi.org/10.1093/noajnl/vdaa093 |
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