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α-Branched amines by catalytic 1,1-addition of C–H bonds and aminating agents to terminal alkenes
α-Branched amines are present in hundreds of pharmaceutical agents and clinical candidates and are important targets for synthesis. Here we show the convergent synthesis of α-branched amines from three readily accessible starting materials: aromatic C–H bond substrates, terminal alkenes, and aminati...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462361/ https://www.ncbi.nlm.nih.gov/pubmed/32879907 http://dx.doi.org/10.1038/s41929-019-0330-7 |