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Noscapine Modulates Neuronal Response to Oxygen-glucose Deprivation/Reperfusion Injury Via Activation of Sigma-1 Receptor in Primary Cortical Cultures

In the present study, we investigated the effects of noscapine (0.5-2 µM), an alkaloid from the opium poppy (Papaver somniferum), on primary murine cortical neurons exposed to 60 min oxygen–glucose deprivation (OGD) in the presence of 5 µM BD-1047, a selective sigma-1 receptor antagonist. The experi...

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Detalles Bibliográficos
Autores principales:	Vahabzadeh, Gelareh, Rahbar-Roshandel, Nahid, Ebrahimi, Soltan-Ahmad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Shaheed Beheshti University of Medical Sciences 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462509/ https://www.ncbi.nlm.nih.gov/pubmed/32922491 http://dx.doi.org/10.22037/ijpr.2019.112317.13683

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