Disruption of the ERLIN–TM6SF2–APOB complex destabilizes APOB and contributes to non-alcoholic fatty liver disease

Non-alcoholic fatty liver disease (NAFLD) is a metabolic disorder characterized by excess lipid accumulation in the liver without significant consumption of alcohol. The transmembrane 6 superfamily member 2 (TM6SF2) E167K missense variant strongly associates with NAFLD in humans. The E167K mutation...

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Detalles Bibliográficos
Autores principales: Li, Bo-Tao, Sun, Ming, Li, Yun-Feng, Wang, Ju-Qiong, Zhou, Zi-Mu, Song, Bao-Liang, Luo, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462549/
https://www.ncbi.nlm.nih.gov/pubmed/32776921
http://dx.doi.org/10.1371/journal.pgen.1008955

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462549/
https://www.ncbi.nlm.nih.gov/pubmed/32776921
http://dx.doi.org/10.1371/journal.pgen.1008955

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