Cargando…
What is the true discharge rate and pattern of the striatal projection neurons in Parkinson’s disease and Dystonia?
Dopamine and striatal dysfunctions play a key role in the pathophysiology of Parkinson’s disease (PD) and Dystonia, but our understanding of the changes in the discharge rate and pattern of striatal projection neurons (SPNs) remains limited. Here, we recorded and examined multi-unit signals from the...
Autores principales: | Valsky, Dan, Heiman Grosberg, Shai, Israel, Zvi, Boraud, Thomas, Bergman, Hagai, Deffains, Marc |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462612/ https://www.ncbi.nlm.nih.gov/pubmed/32812870 http://dx.doi.org/10.7554/eLife.57445 |
Ejemplares similares
-
Subthalamic, not striatal, activity correlates with basal ganglia downstream activity in normal and parkinsonian monkeys
por: Deffains, Marc, et al.
Publicado: (2016) -
Different correlation patterns of cholinergic and GABAergic interneurons with striatal projection neurons
por: Adler, Avital, et al.
Publicado: (2013) -
Independently together: subthalamic theta and beta opposite roles in predicting Parkinson’s tremor
por: Asch, Nir, et al.
Publicado: (2020) -
Deep brain stimulation modulates nonsense-mediated RNA decay in Parkinson’s patients leukocytes
por: Soreq, Lilach, et al.
Publicado: (2013) -
Cell type-specific plasticity of striatal projection neurons in parkinsonism and L-DOPA-induced dyskinesia
por: Fieblinger, Tim, et al.
Publicado: (2014)