Cargando…

The Impact of Physician Face Mask Use on Endophthalmitis After Intravitreal Anti–Vascular Endothelial Growth Factor Injections

PURPOSE: To evaluate the effect of physician face mask use on rates and outcomes of postinjection endophthalmitis. DESIGN: Retrospective, comparative cohort study. METHODS: Setting: Single-center. StudyPopulation: Eyes receiving intravitreal anti–vascular endothelial growth factor injections from Ju...

Descripción completa

Detalles Bibliográficos
Autores principales: Patel, Samir N., Hsu, Jason, Sivalingam, Meera D., Chiang, Allen, Kaiser, Richard S., Mehta, Sonia, Park, Carl H., Regillo, Carl D., Sivalingam, Arunan, Vander, James F., Ho, Allen C., Garg, Sunir J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462768/
https://www.ncbi.nlm.nih.gov/pubmed/32888902
http://dx.doi.org/10.1016/j.ajo.2020.08.013
_version_ 1783576986198736896
author Patel, Samir N.
Hsu, Jason
Sivalingam, Meera D.
Chiang, Allen
Kaiser, Richard S.
Mehta, Sonia
Park, Carl H.
Regillo, Carl D.
Sivalingam, Arunan
Vander, James F.
Ho, Allen C.
Garg, Sunir J.
author_facet Patel, Samir N.
Hsu, Jason
Sivalingam, Meera D.
Chiang, Allen
Kaiser, Richard S.
Mehta, Sonia
Park, Carl H.
Regillo, Carl D.
Sivalingam, Arunan
Vander, James F.
Ho, Allen C.
Garg, Sunir J.
author_sort Patel, Samir N.
collection PubMed
description PURPOSE: To evaluate the effect of physician face mask use on rates and outcomes of postinjection endophthalmitis. DESIGN: Retrospective, comparative cohort study. METHODS: Setting: Single-center. StudyPopulation: Eyes receiving intravitreal anti–vascular endothelial growth factor injections from July 1, 2013, to September 1, 2019. Intervention: Cases were divided into “Face Mask” group if face masks were worn by the physician during intravitreal injections or “No Talking” group if no face mask was worn but a no-talking policy was observed during intravitreal injections. MainOutcomeMeasures: Rate of endophthalmitis, visual acuity, and microbial spectrum. RESULTS: Of 483,622 intravitreal injections administered, 168 out of 453,460 (0.0371%) cases of endophthalmitis occurred in the No Talking group, and 9 out of 30,162 (0.0298%) cases occurred in the Face Mask group (odds ratio, 0.81; 95% confidence interval, 0.41-1.57; P = .527). Sixteen cases of oral flora–associated endophthalmitis were found in the No Talking group (1 in 28,341 injections), compared to none in the Face Mask group (P = .302). Mean logMAR visual acuity at presentation in cases that developed culture-positive endophthalmitis was significantly worse in the No Talking group compared to the Face Mask group (17.1 lines lost from baseline acuity vs 13.4 lines lost; P = .031), though no difference was observed at 6 months after treatment (P = .479). CONCLUSION: Physician face mask use did not influence the risk of postinjection endophthalmitis compared to a no-talking policy. However, no cases of oral flora–associated endophthalmitis occurred in the Face Mask group. Future studies are warranted to assess the role of face mask use to reduce endophthalmitis risk, particularly attributable to oral flora.
format Online
Article
Text
id pubmed-7462768
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Elsevier Inc.
record_format MEDLINE/PubMed
spelling pubmed-74627682020-09-02 The Impact of Physician Face Mask Use on Endophthalmitis After Intravitreal Anti–Vascular Endothelial Growth Factor Injections Patel, Samir N. Hsu, Jason Sivalingam, Meera D. Chiang, Allen Kaiser, Richard S. Mehta, Sonia Park, Carl H. Regillo, Carl D. Sivalingam, Arunan Vander, James F. Ho, Allen C. Garg, Sunir J. Am J Ophthalmol Original Article PURPOSE: To evaluate the effect of physician face mask use on rates and outcomes of postinjection endophthalmitis. DESIGN: Retrospective, comparative cohort study. METHODS: Setting: Single-center. StudyPopulation: Eyes receiving intravitreal anti–vascular endothelial growth factor injections from July 1, 2013, to September 1, 2019. Intervention: Cases were divided into “Face Mask” group if face masks were worn by the physician during intravitreal injections or “No Talking” group if no face mask was worn but a no-talking policy was observed during intravitreal injections. MainOutcomeMeasures: Rate of endophthalmitis, visual acuity, and microbial spectrum. RESULTS: Of 483,622 intravitreal injections administered, 168 out of 453,460 (0.0371%) cases of endophthalmitis occurred in the No Talking group, and 9 out of 30,162 (0.0298%) cases occurred in the Face Mask group (odds ratio, 0.81; 95% confidence interval, 0.41-1.57; P = .527). Sixteen cases of oral flora–associated endophthalmitis were found in the No Talking group (1 in 28,341 injections), compared to none in the Face Mask group (P = .302). Mean logMAR visual acuity at presentation in cases that developed culture-positive endophthalmitis was significantly worse in the No Talking group compared to the Face Mask group (17.1 lines lost from baseline acuity vs 13.4 lines lost; P = .031), though no difference was observed at 6 months after treatment (P = .479). CONCLUSION: Physician face mask use did not influence the risk of postinjection endophthalmitis compared to a no-talking policy. However, no cases of oral flora–associated endophthalmitis occurred in the Face Mask group. Future studies are warranted to assess the role of face mask use to reduce endophthalmitis risk, particularly attributable to oral flora. Elsevier Inc. 2021-02 2020-09-02 /pmc/articles/PMC7462768/ /pubmed/32888902 http://dx.doi.org/10.1016/j.ajo.2020.08.013 Text en © 2020 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Original Article
Patel, Samir N.
Hsu, Jason
Sivalingam, Meera D.
Chiang, Allen
Kaiser, Richard S.
Mehta, Sonia
Park, Carl H.
Regillo, Carl D.
Sivalingam, Arunan
Vander, James F.
Ho, Allen C.
Garg, Sunir J.
The Impact of Physician Face Mask Use on Endophthalmitis After Intravitreal Anti–Vascular Endothelial Growth Factor Injections
title The Impact of Physician Face Mask Use on Endophthalmitis After Intravitreal Anti–Vascular Endothelial Growth Factor Injections
title_full The Impact of Physician Face Mask Use on Endophthalmitis After Intravitreal Anti–Vascular Endothelial Growth Factor Injections
title_fullStr The Impact of Physician Face Mask Use on Endophthalmitis After Intravitreal Anti–Vascular Endothelial Growth Factor Injections
title_full_unstemmed The Impact of Physician Face Mask Use on Endophthalmitis After Intravitreal Anti–Vascular Endothelial Growth Factor Injections
title_short The Impact of Physician Face Mask Use on Endophthalmitis After Intravitreal Anti–Vascular Endothelial Growth Factor Injections
title_sort impact of physician face mask use on endophthalmitis after intravitreal anti–vascular endothelial growth factor injections
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462768/
https://www.ncbi.nlm.nih.gov/pubmed/32888902
http://dx.doi.org/10.1016/j.ajo.2020.08.013
work_keys_str_mv AT patelsamirn theimpactofphysicianfacemaskuseonendophthalmitisafterintravitrealantivascularendothelialgrowthfactorinjections
AT hsujason theimpactofphysicianfacemaskuseonendophthalmitisafterintravitrealantivascularendothelialgrowthfactorinjections
AT sivalingammeerad theimpactofphysicianfacemaskuseonendophthalmitisafterintravitrealantivascularendothelialgrowthfactorinjections
AT chiangallen theimpactofphysicianfacemaskuseonendophthalmitisafterintravitrealantivascularendothelialgrowthfactorinjections
AT kaiserrichards theimpactofphysicianfacemaskuseonendophthalmitisafterintravitrealantivascularendothelialgrowthfactorinjections
AT mehtasonia theimpactofphysicianfacemaskuseonendophthalmitisafterintravitrealantivascularendothelialgrowthfactorinjections
AT parkcarlh theimpactofphysicianfacemaskuseonendophthalmitisafterintravitrealantivascularendothelialgrowthfactorinjections
AT regillocarld theimpactofphysicianfacemaskuseonendophthalmitisafterintravitrealantivascularendothelialgrowthfactorinjections
AT sivalingamarunan theimpactofphysicianfacemaskuseonendophthalmitisafterintravitrealantivascularendothelialgrowthfactorinjections
AT vanderjamesf theimpactofphysicianfacemaskuseonendophthalmitisafterintravitrealantivascularendothelialgrowthfactorinjections
AT hoallenc theimpactofphysicianfacemaskuseonendophthalmitisafterintravitrealantivascularendothelialgrowthfactorinjections
AT gargsunirj theimpactofphysicianfacemaskuseonendophthalmitisafterintravitrealantivascularendothelialgrowthfactorinjections
AT patelsamirn impactofphysicianfacemaskuseonendophthalmitisafterintravitrealantivascularendothelialgrowthfactorinjections
AT hsujason impactofphysicianfacemaskuseonendophthalmitisafterintravitrealantivascularendothelialgrowthfactorinjections
AT sivalingammeerad impactofphysicianfacemaskuseonendophthalmitisafterintravitrealantivascularendothelialgrowthfactorinjections
AT chiangallen impactofphysicianfacemaskuseonendophthalmitisafterintravitrealantivascularendothelialgrowthfactorinjections
AT kaiserrichards impactofphysicianfacemaskuseonendophthalmitisafterintravitrealantivascularendothelialgrowthfactorinjections
AT mehtasonia impactofphysicianfacemaskuseonendophthalmitisafterintravitrealantivascularendothelialgrowthfactorinjections
AT parkcarlh impactofphysicianfacemaskuseonendophthalmitisafterintravitrealantivascularendothelialgrowthfactorinjections
AT regillocarld impactofphysicianfacemaskuseonendophthalmitisafterintravitrealantivascularendothelialgrowthfactorinjections
AT sivalingamarunan impactofphysicianfacemaskuseonendophthalmitisafterintravitrealantivascularendothelialgrowthfactorinjections
AT vanderjamesf impactofphysicianfacemaskuseonendophthalmitisafterintravitrealantivascularendothelialgrowthfactorinjections
AT hoallenc impactofphysicianfacemaskuseonendophthalmitisafterintravitrealantivascularendothelialgrowthfactorinjections
AT gargsunirj impactofphysicianfacemaskuseonendophthalmitisafterintravitrealantivascularendothelialgrowthfactorinjections