Cargando…

Examining treatment responses of diagnostic marrow in murine xenografts to predict relapse in children with acute lymphoblastic leukaemia

BACKGROUND: While current chemotherapy has increased cure rates for children with acute lymphoblastic leukaemia (ALL), the largest number of relapsing patients are still stratified as medium risk (MR) at diagnosis (50–60%). This highlights an opportunity to develop improved relapse-prediction models...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alruwetei, Abdulmohsen M., Bendak, Katerina, Yadav, Babasaheb D., Carol, Hernan, Evans, Kathryn, Mayoh, Chelsea, Sutton, Rosemary, Marshall, Glenn M., Lock, Richard B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462974/ https://www.ncbi.nlm.nih.gov/pubmed/32536690 http://dx.doi.org/10.1038/s41416-020-0933-4

Ejemplares similares

Heterogeneity in mechanisms of emergent resistance in pediatric T-cell acute lymphoblastic leukemia
por: Yadav, Babasaheb D., et al.
Publicado: (2016)

Reversal of glucocorticoid resistance in paediatric acute lymphoblastic leukaemia is dependent on restoring BIM expression
por: Toscan, Cara E., et al.
Publicado: (2020)

Marrow relapse on maintenance chemotherapy in childhood acute lymphoblastic leukaemia.
por: Kearney, P. J., et al.
Publicado: (1979)

Validation of a mouse xenograft model system for gene expression analysis of human acute lymphoblastic leukaemia
por: Samuels, Amy L, et al.
Publicado: (2010)

Whole-genome sequencing facilitates patient-specific quantitative PCR-based minimal residual disease monitoring in acute lymphoblastic leukaemia, neuroblastoma and Ewing sarcoma
por: Subhash, Vinod Vijay, et al.
Publicado: (2021)

Measurable residual disease analysis in paediatric acute lymphoblastic leukaemia patients with ABL-class fusions
por: Venn, Nicola C., et al.
Publicado: (2022)

Outcomes of patients with childhood B-cell precursor acute lymphoblastic leukaemia with late bone marrow relapses: long-term follow-up of the ALLR3 open-label randomised trial
por: Parker, Catriona, et al.
Publicado: (2019)

Testicular relapse in acute lymphoblastic leukaemia: studies with an experimental mouse model.
por: Jackson, H., et al.
Publicado: (1984)

Effect of mitoxantrone on outcome of children with first relapse of acute lymphoblastic leukaemia (ALL R3): an open-label randomised trial
por: Parker, Catriona, et al.
Publicado: (2010)

Mechanisms of relapse in acute leukaemia: involvement of p53 mutated subclones in disease progression in acute lymphoblastic leukaemia
por: Zhu, Y-M, et al.
Publicado: (1999)

Outcome of Central Nervous System Relapses In Childhood Acute Lymphoblastic Leukaemia – Prospective Open Cohort Analyses of the ALLR3 Trial
por: Masurekar, Ashish Narayan, et al.
Publicado: (2014)

Extensive Bone Marrow Necrosis: A Rare Presentation of Acute Lymphoblastic Leukaemia
por: Ranathunga, I., et al.
Publicado: (2020)

Stability of gene expression and epigenetic profiles highlights the utility of patient-derived paediatric acute lymphoblastic leukaemia xenografts for investigating molecular mechanisms of drug resistance
por: Wong, Nicholas C, et al.
Publicado: (2014)

Pre-B acute lymphoblastic leukaemia recurrent fusion, EP300-ZNF384, is associated with a distinct gene expression
por: McClure, Barbara J., et al.
Publicado: (2018)

French “real life” experience of clofarabine in children with refractory or relapsed acute lymphoblastic leukaemia
por: Trioche, Pascale, et al.
Publicado: (2012)

Rise and fall of subclones from diagnosis to relapse in pediatric B-acute lymphoblastic leukaemia
por: Ma, Xiaotu, et al.
Publicado: (2015)

Pharmacokinetic Modeling of an Induction Regimen for In Vivo Combined Testing of Novel Drugs against Pediatric Acute Lymphoblastic Leukemia Xenografts
por: Szymanska, Barbara, et al.
Publicado: (2012)

RaScALL: Rapid (Ra) screening (Sc) of RNA-seq data for prognostically significant genomic alterations in acute lymphoblastic leukaemia (ALL)
por: Rehn, Jacqueline, et al.
Publicado: (2022)

Extramedullary Gastric Relapse at the Time of Bone Marrow Relapse of Acute Lymphoblastic Leukemia after Allogeneic Bone Marrow Transplantation
por: Ikeuchi, Kazuhiko, et al.
Publicado: (2017)

Acute disseminated encephalomyelitis mimicking late CNS relapse of acute lymphoblastic leukaemia: case report
por: Kumar, Ram, et al.
Publicado: (2007)

The shape of cancer relapse: Topological data analysis predicts recurrence in paediatric acute lymphoblastic leukaemia
por: Chulián, Salvador, et al.
Publicado: (2023)

Prognostic relevance of pretreatment proliferative rapidity of marrow blast cells in childhood acute lymphoblastic leukaemia.
por: Trerè, D., et al.
Publicado: (1994)

Regulation of the bone marrow microenvironment by G-CSF: Effects of G-CSF on acute lymphoblastic leukaemia
por: Basnett, Jordan, et al.
Publicado: (2017)

P342: RAS PATHWAY ACTIVATION REMODELS THE BONE MARROW MICROENVIRONMENT IN ACUTE LYMPHOBLASTIC LEUKAEMIA
por: Ferrao Blanco, Mauricio, et al.
Publicado: (2023)

Clonal selection in xenografted human T cell acute lymphoblastic leukemia recapitulates gain of malignancy at relapse
por: Clappier, Emmanuelle, et al.
Publicado: (2011)

Genome-wide DNA methylation profiling predicts relapse in childhood B-cell acute lymphoblastic leukaemia
por: Sandoval, Juan, et al.
Publicado: (2013)

Isolated myocardial relapse of Philadelphia-positive acute lymphoblastic leukaemia causing myocarditis: a case report
por: Nadel, James, et al.
Publicado: (2018)

T lymphoblastic leukaemia and the central nervous system.
por: Lilleyman, J. S., et al.
Publicado: (1981)

Long survival in childhood lymphoblastic leukaemia.
por: Chessells, J. M., et al.
Publicado: (1987)

Inotuzumab ozogamicin for acute lymphoblastic leukaemia
Publicado: (2019)

Targeted Therapy in Acute Lymphoblastic Leukaemia
por: Salvaris, Ross, et al.
Publicado: (2021)

Relationship between the pretreatment proliferative activity of marrow blast cells and prognosis of acute lymphoblastic leukaemia of childhood
por: Scarffe, J. H., et al.
Publicado: (1980)

Non‐tumour bone marrow lymphocytes correlate with improved overall survival in childhood acute lymphoblastic leukaemia
por: Edwin, Claire, et al.
Publicado: (2016)

Different types of non-P-glycoprotein mediated multiple drug resistance in children with relapsed acute lymphoblastic leukaemia.
por: Pieters, R., et al.
Publicado: (1992)

Exposure–response analysis of blinatumomab in patients with relapsed/refractory acute lymphoblastic leukaemia and comparison with standard of care chemotherapy
por: Kuchimanchi, Mita, et al.
Publicado: (2019)

High-Dimensional Analysis of Single-Cell Flow Cytometry Data Predicts Relapse in Childhood Acute Lymphoblastic Leukaemia
por: Chulián, Salvador, et al.
Publicado: (2020)

Subgrouping by gene expression profiles to improve relapse risk prediction in paediatric B‐precursor acute lymphoblastic leukaemia
por: Huang, Qingsheng, et al.
Publicado: (2021)

Bone Marrow Recovery by Morphometry during Induction Chemotherapy for Acute Lymphoblastic Leukemia in Children
por: Nguyen, Tuong-Vi, et al.
Publicado: (2015)

Effect of Aplidin in acute lymphoblastic leukaemia cells
por: Erba, E, et al.
Publicado: (2003)

Cytotoxicity of tamoxifen for acute lymphoblastic leukaemia in vitro.
por: Blatt, J., et al.
Publicado: (1984)

Cannot write session to /tmp/vufind_sessions/sess_in9q13gh5vab2ifv4lgq5p0kdk