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Ibuprofen mediates histone modification to diminish cancer cell stemness properties via a COX2-dependent manner
BACKGROUND: The anticancer potential of ibuprofen has created a broad interest to explore the clinical benefits of ibuprofen in cancer therapy. However, the current understanding of the molecular mechanisms involved in the anticancer potential of ibuprofen remains limited. METHODS: Cancer stemness a...
Autores principales: | Shen, Wenzhi, Zhang, Xiaoyuan, Du, Renle, Gao, Wenjuan, Wang, Juan, Bao, Yonghua, Yang, Wancai, Luo, Na, Li, Jianjun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463005/ https://www.ncbi.nlm.nih.gov/pubmed/32528119 http://dx.doi.org/10.1038/s41416-020-0906-7 |
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