Identification of de novo mutations in prenatal neurodevelopment-associated genes in schizophrenia in two Han Chinese patient-sibling family-based cohorts

Schizophrenia (SCZ) is a severe psychiatric disorder with a strong genetic component. High heritability of SCZ suggests a major role for transmitted genetic variants. Furthermore, SCZ is also associated with a marked reduction in fecundity, leading to the hypothesis that alleles with large effects o...

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Detalles Bibliográficos
Autores principales: Jiang, Shan, Zhou, Daizhan, Wang, Yin-Ying, Jia, Peilin, Wan, Chunling, Li, Xingwang, He, Guang, Cao, Dongmei, Jiang, Xiaoqian, Kendler, Kenneth S., Tsuang, Ming, Mize, Travis, Wu, Jain-Shing, Lu, Yimei, He, Lin, Chen, Jingchun, Zhao, Zhongming, Chen, Xiangning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463022/
https://www.ncbi.nlm.nih.gov/pubmed/32873781
http://dx.doi.org/10.1038/s41398-020-00987-z

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