ASCL1-regulated DARPP-32 and t-DARPP stimulate small cell lung cancer growth and neuroendocrine tumour cell proliferation

BACKGROUND: Small cell lung cancer (SCLC) is the most aggressive form of lung cancer, and new molecular insights are necessary for prognostic and therapeutic advances. METHODS: Dopamine and cAMP-regulated phosphoprotein, Mr 32000 (DARPP-32) and its N-terminally truncated splice variant, t-DARPP, wer...

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Detalles Bibliográficos
Autores principales: Alam, Sk. Kayum, Wang, Li, Ren, Yanan, Hernandez, Christina E., Kosari, Farhad, Roden, Anja C., Yang, Rendong, Hoeppner, Luke H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463034/
https://www.ncbi.nlm.nih.gov/pubmed/32499571
http://dx.doi.org/10.1038/s41416-020-0923-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463034/
https://www.ncbi.nlm.nih.gov/pubmed/32499571
http://dx.doi.org/10.1038/s41416-020-0923-6

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