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GLUT3 induced by AMPK/CREB1 axis is key for withstanding energy stress and augments the efficacy of current colorectal cancer therapies

Cancer cells are usually characterized by hyperactive glucose metabolism, which can often lead to glucose scarcity; thus, alternative pathways to rewire cancer metabolism are required. Here, we demonstrated that GLUT3 was highly expressed in colorectal cancer (CRC) and negatively linked to CRC patie...

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Detalles Bibliográficos
Autores principales: Dai, Weixing, Xu, Ye, Mo, Shaobo, Li, Qingguo, Yu, Jun, Wang, Renjie, Ma, Yanlei, Ni, Yan, Xiang, Wenqiang, Han, Lingyu, Zhang, Long, Cai, Sanjun, Qin, Jun, Chen, Wen-Lian, Jia, Wei, Cai, Guoxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463260/
https://www.ncbi.nlm.nih.gov/pubmed/32873793
http://dx.doi.org/10.1038/s41392-020-00220-9