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Promoter Proximal Pausing Limits Tumorous Growth Induced by the Yki Transcription Factor in Drosophila

Promoter proximal pausing (PPP) of RNA polymerase II has emerged as a crucial rate-limiting step in the regulation of gene expression. Regulation of PPP is brought about by complexes 7SK snRNP, P-TEFb (Cdk9/cycT), and the negative elongation factor (NELF), which are highly conserved from Drosophila...

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Detalles Bibliográficos
Autores principales:	Nagarkar, Sanket, Wasnik, Ruchi, Govada, Pravallika, Cohen, Stephen, Shashidhara, L. S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2020
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463282/ https://www.ncbi.nlm.nih.gov/pubmed/32737120 http://dx.doi.org/10.1534/genetics.120.303419

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