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Prevalence of PRKDC mutations and association with response to immune checkpoint inhibitors in solid tumors

Predictive biomarkers of response to immune checkpoint inhibitors (ICI) help to identify cancer patients who will benefit from immunotherapy. Protein kinase, DNA‐activated, catalytic subunit (PRKDC) is an important gene for DNA double‐strand break (DSB) repair and central T‐cell tolerance. We aimed...

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Detalles Bibliográficos
Autores principales:	Chen, Yu, Li, Yi, Guan, Yanfang, Huang, Yingying, Lin, Jing, Chen, Lizhu, Li, Jin, Chen, Gang, Pan, Leong Kin, Xia, Xuefeng, Xu, Ning, Chang, Lianpeng, Guo, Zengqing, Pan, Jianji, Yi, Xin, Chen, Chuanben
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463346/ https://www.ncbi.nlm.nih.gov/pubmed/32502294 http://dx.doi.org/10.1002/1878-0261.12739

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