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Characterization of PHGDH expression in bladder cancer: potential targeting therapy with gemcitabine/cisplatin and the contribution of promoter DNA hypomethylation

d‐3‐Phosphoglycerate dehydrogenase (PHGDH) conducts an important step in the synthesis of serine. Importantly, the PHGDH gene is often amplified in certain cancers. Our previous studies revealed that PHGDH gene amplification was associated with poor overall survival in clear cell renal cell carcinom...

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Detalles Bibliográficos
Autores principales:	Yoshino, Hirofumi, Enokida, Hideki, Osako, Yoichi, Nohata, Nijiro, Yonemori, Masaya, Sugita, Satoshi, Kuroshima, Kazuki, Tsuruda, Masafumi, Tatarano, Shuichi, Nakagawa, Masayuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463350/ https://www.ncbi.nlm.nih.gov/pubmed/32386122 http://dx.doi.org/10.1002/1878-0261.12697

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