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Inhibition of TLR4 Signaling Affects Mitochondrial Fitness and Overcomes Bortezomib Resistance in Myeloma Plasma Cells

Multiple myeloma (MM) is a B-cell malignancy requiring inflammatory microenvironment signals for cell survival and proliferation. Despite improvements in pharmacological tools, MM remains incurable mainly because of drug resistance. The present study aimed to investigate the implication of Toll-like...

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Detalles Bibliográficos
Autores principales: Giallongo, Cesarina, Tibullo, Daniele, Puglisi, Fabrizio, Barbato, Alessandro, Vicario, Nunzio, Cambria, Daniela, Parrinello, Nunziatina Laura, Romano, Alessandra, Conticello, Concetta, Forte, Stefano, Parenti, Rosalba, Amorini, Angela Maria, Lazzarino, Giuseppe, Li Volti, Giovanni, Palumbo, Giuseppe Alberto, Di Raimondo, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463509/
https://www.ncbi.nlm.nih.gov/pubmed/32707760
http://dx.doi.org/10.3390/cancers12081999