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Distinct Mechanisms Are Responsible for Nrf2-Keap1 Pathway Activation at Different Stages of Rat Hepatocarcinogenesis

Activation of the Nrf2-Keap1 pathway, the main intracellular defense against environmental stress, has been observed in several human cancers, including hepatocellular carcinoma (HCC). Here, we assessed whether distinct mechanisms of activation may be involved at different stages of hepatocarcinogen...

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Detalles Bibliográficos
Autores principales:	Orrù, Claudia, Perra, Andrea, Kowalik, Marta Anna, Rizzolio, Sabrina, Puliga, Elisabetta, Cabras, Lavinia, Giordano, Silvia, Columbano, Amedeo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463589/ https://www.ncbi.nlm.nih.gov/pubmed/32824383 http://dx.doi.org/10.3390/cancers12082305

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