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Ablation of Atrial Fibrillation in Patients with Hypertension—An Analysis from the German Ablation Registry

Background: Hypertension (HTN) constitutes a risk factor for the development of atrial fibrillation (AF), as well as for thromboembolic and bleeding events. We analysed the outcome after catheter ablation of AF in HTN in a cohort from the prospective multicenter German Ablation Registry. Methods: Be...

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Autores principales: Zylla, Maura M., Hochadel, Matthias, Andresen, Dietrich, Brachmann, Johannes, Eckardt, Lars, Hoffmann, Ellen, Kuck, Karl-Heinz, Lewalter, Thorsten, Schumacher, Burghard, Spitzer, Stefan G., Willems, Stephan, Senges, Jochen, Katus, Hugo A., Thomas, Dierk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463680/
https://www.ncbi.nlm.nih.gov/pubmed/32727136
http://dx.doi.org/10.3390/jcm9082402
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author Zylla, Maura M.
Hochadel, Matthias
Andresen, Dietrich
Brachmann, Johannes
Eckardt, Lars
Hoffmann, Ellen
Kuck, Karl-Heinz
Lewalter, Thorsten
Schumacher, Burghard
Spitzer, Stefan G.
Willems, Stephan
Senges, Jochen
Katus, Hugo A.
Thomas, Dierk
author_facet Zylla, Maura M.
Hochadel, Matthias
Andresen, Dietrich
Brachmann, Johannes
Eckardt, Lars
Hoffmann, Ellen
Kuck, Karl-Heinz
Lewalter, Thorsten
Schumacher, Burghard
Spitzer, Stefan G.
Willems, Stephan
Senges, Jochen
Katus, Hugo A.
Thomas, Dierk
author_sort Zylla, Maura M.
collection PubMed
description Background: Hypertension (HTN) constitutes a risk factor for the development of atrial fibrillation (AF), as well as for thromboembolic and bleeding events. We analysed the outcome after catheter ablation of AF in HTN in a cohort from the prospective multicenter German Ablation Registry. Methods: Between 03/2008 and 01/2010, 626 patients undergoing AF-ablation were analysed. Patients diagnosed with HTN (n = 386) were compared with patients without HTN (n = 240) with respect to baseline, procedural and long-term outcome parameters. Results: Patients with HTN were older and more often presented with persistent forms of AF and cardiac comorbidities. Major and moderate in-hospital complications were low. At long-term follow-up, major cardiovascular events were rare in both groups. Rates of AF-recurrence, freedom from antiarrhythmic medication and repeat ablation were not statistically different between groups. Most patients reported improvement of symptoms and satisfaction with the treatment. However, patients with HTN more frequently complained of dyspnea of New York Heart Association (NYHA) class ≥ II and angina. They were more often rehospitalized, particularly when persistent AF had been diagnosed. Conclusion: Catheter ablation of AF is associated with low complication rates and favorable arrhythmia-related results in patients with HTN. Residual clinical symptoms may be due to cardiac comorbidities and require additional attention in this important subgroup of AF-patients.
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spelling pubmed-74636802020-09-02 Ablation of Atrial Fibrillation in Patients with Hypertension—An Analysis from the German Ablation Registry Zylla, Maura M. Hochadel, Matthias Andresen, Dietrich Brachmann, Johannes Eckardt, Lars Hoffmann, Ellen Kuck, Karl-Heinz Lewalter, Thorsten Schumacher, Burghard Spitzer, Stefan G. Willems, Stephan Senges, Jochen Katus, Hugo A. Thomas, Dierk J Clin Med Article Background: Hypertension (HTN) constitutes a risk factor for the development of atrial fibrillation (AF), as well as for thromboembolic and bleeding events. We analysed the outcome after catheter ablation of AF in HTN in a cohort from the prospective multicenter German Ablation Registry. Methods: Between 03/2008 and 01/2010, 626 patients undergoing AF-ablation were analysed. Patients diagnosed with HTN (n = 386) were compared with patients without HTN (n = 240) with respect to baseline, procedural and long-term outcome parameters. Results: Patients with HTN were older and more often presented with persistent forms of AF and cardiac comorbidities. Major and moderate in-hospital complications were low. At long-term follow-up, major cardiovascular events were rare in both groups. Rates of AF-recurrence, freedom from antiarrhythmic medication and repeat ablation were not statistically different between groups. Most patients reported improvement of symptoms and satisfaction with the treatment. However, patients with HTN more frequently complained of dyspnea of New York Heart Association (NYHA) class ≥ II and angina. They were more often rehospitalized, particularly when persistent AF had been diagnosed. Conclusion: Catheter ablation of AF is associated with low complication rates and favorable arrhythmia-related results in patients with HTN. Residual clinical symptoms may be due to cardiac comorbidities and require additional attention in this important subgroup of AF-patients. MDPI 2020-07-27 /pmc/articles/PMC7463680/ /pubmed/32727136 http://dx.doi.org/10.3390/jcm9082402 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zylla, Maura M.
Hochadel, Matthias
Andresen, Dietrich
Brachmann, Johannes
Eckardt, Lars
Hoffmann, Ellen
Kuck, Karl-Heinz
Lewalter, Thorsten
Schumacher, Burghard
Spitzer, Stefan G.
Willems, Stephan
Senges, Jochen
Katus, Hugo A.
Thomas, Dierk
Ablation of Atrial Fibrillation in Patients with Hypertension—An Analysis from the German Ablation Registry
title Ablation of Atrial Fibrillation in Patients with Hypertension—An Analysis from the German Ablation Registry
title_full Ablation of Atrial Fibrillation in Patients with Hypertension—An Analysis from the German Ablation Registry
title_fullStr Ablation of Atrial Fibrillation in Patients with Hypertension—An Analysis from the German Ablation Registry
title_full_unstemmed Ablation of Atrial Fibrillation in Patients with Hypertension—An Analysis from the German Ablation Registry
title_short Ablation of Atrial Fibrillation in Patients with Hypertension—An Analysis from the German Ablation Registry
title_sort ablation of atrial fibrillation in patients with hypertension—an analysis from the german ablation registry
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463680/
https://www.ncbi.nlm.nih.gov/pubmed/32727136
http://dx.doi.org/10.3390/jcm9082402
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