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Ablation of Atrial Fibrillation in Patients with Hypertension—An Analysis from the German Ablation Registry
Background: Hypertension (HTN) constitutes a risk factor for the development of atrial fibrillation (AF), as well as for thromboembolic and bleeding events. We analysed the outcome after catheter ablation of AF in HTN in a cohort from the prospective multicenter German Ablation Registry. Methods: Be...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463680/ https://www.ncbi.nlm.nih.gov/pubmed/32727136 http://dx.doi.org/10.3390/jcm9082402 |
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author | Zylla, Maura M. Hochadel, Matthias Andresen, Dietrich Brachmann, Johannes Eckardt, Lars Hoffmann, Ellen Kuck, Karl-Heinz Lewalter, Thorsten Schumacher, Burghard Spitzer, Stefan G. Willems, Stephan Senges, Jochen Katus, Hugo A. Thomas, Dierk |
author_facet | Zylla, Maura M. Hochadel, Matthias Andresen, Dietrich Brachmann, Johannes Eckardt, Lars Hoffmann, Ellen Kuck, Karl-Heinz Lewalter, Thorsten Schumacher, Burghard Spitzer, Stefan G. Willems, Stephan Senges, Jochen Katus, Hugo A. Thomas, Dierk |
author_sort | Zylla, Maura M. |
collection | PubMed |
description | Background: Hypertension (HTN) constitutes a risk factor for the development of atrial fibrillation (AF), as well as for thromboembolic and bleeding events. We analysed the outcome after catheter ablation of AF in HTN in a cohort from the prospective multicenter German Ablation Registry. Methods: Between 03/2008 and 01/2010, 626 patients undergoing AF-ablation were analysed. Patients diagnosed with HTN (n = 386) were compared with patients without HTN (n = 240) with respect to baseline, procedural and long-term outcome parameters. Results: Patients with HTN were older and more often presented with persistent forms of AF and cardiac comorbidities. Major and moderate in-hospital complications were low. At long-term follow-up, major cardiovascular events were rare in both groups. Rates of AF-recurrence, freedom from antiarrhythmic medication and repeat ablation were not statistically different between groups. Most patients reported improvement of symptoms and satisfaction with the treatment. However, patients with HTN more frequently complained of dyspnea of New York Heart Association (NYHA) class ≥ II and angina. They were more often rehospitalized, particularly when persistent AF had been diagnosed. Conclusion: Catheter ablation of AF is associated with low complication rates and favorable arrhythmia-related results in patients with HTN. Residual clinical symptoms may be due to cardiac comorbidities and require additional attention in this important subgroup of AF-patients. |
format | Online Article Text |
id | pubmed-7463680 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-74636802020-09-02 Ablation of Atrial Fibrillation in Patients with Hypertension—An Analysis from the German Ablation Registry Zylla, Maura M. Hochadel, Matthias Andresen, Dietrich Brachmann, Johannes Eckardt, Lars Hoffmann, Ellen Kuck, Karl-Heinz Lewalter, Thorsten Schumacher, Burghard Spitzer, Stefan G. Willems, Stephan Senges, Jochen Katus, Hugo A. Thomas, Dierk J Clin Med Article Background: Hypertension (HTN) constitutes a risk factor for the development of atrial fibrillation (AF), as well as for thromboembolic and bleeding events. We analysed the outcome after catheter ablation of AF in HTN in a cohort from the prospective multicenter German Ablation Registry. Methods: Between 03/2008 and 01/2010, 626 patients undergoing AF-ablation were analysed. Patients diagnosed with HTN (n = 386) were compared with patients without HTN (n = 240) with respect to baseline, procedural and long-term outcome parameters. Results: Patients with HTN were older and more often presented with persistent forms of AF and cardiac comorbidities. Major and moderate in-hospital complications were low. At long-term follow-up, major cardiovascular events were rare in both groups. Rates of AF-recurrence, freedom from antiarrhythmic medication and repeat ablation were not statistically different between groups. Most patients reported improvement of symptoms and satisfaction with the treatment. However, patients with HTN more frequently complained of dyspnea of New York Heart Association (NYHA) class ≥ II and angina. They were more often rehospitalized, particularly when persistent AF had been diagnosed. Conclusion: Catheter ablation of AF is associated with low complication rates and favorable arrhythmia-related results in patients with HTN. Residual clinical symptoms may be due to cardiac comorbidities and require additional attention in this important subgroup of AF-patients. MDPI 2020-07-27 /pmc/articles/PMC7463680/ /pubmed/32727136 http://dx.doi.org/10.3390/jcm9082402 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Zylla, Maura M. Hochadel, Matthias Andresen, Dietrich Brachmann, Johannes Eckardt, Lars Hoffmann, Ellen Kuck, Karl-Heinz Lewalter, Thorsten Schumacher, Burghard Spitzer, Stefan G. Willems, Stephan Senges, Jochen Katus, Hugo A. Thomas, Dierk Ablation of Atrial Fibrillation in Patients with Hypertension—An Analysis from the German Ablation Registry |
title | Ablation of Atrial Fibrillation in Patients with Hypertension—An Analysis from the German Ablation Registry |
title_full | Ablation of Atrial Fibrillation in Patients with Hypertension—An Analysis from the German Ablation Registry |
title_fullStr | Ablation of Atrial Fibrillation in Patients with Hypertension—An Analysis from the German Ablation Registry |
title_full_unstemmed | Ablation of Atrial Fibrillation in Patients with Hypertension—An Analysis from the German Ablation Registry |
title_short | Ablation of Atrial Fibrillation in Patients with Hypertension—An Analysis from the German Ablation Registry |
title_sort | ablation of atrial fibrillation in patients with hypertension—an analysis from the german ablation registry |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463680/ https://www.ncbi.nlm.nih.gov/pubmed/32727136 http://dx.doi.org/10.3390/jcm9082402 |
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