Impact of Host, Lifestyle and Environmental Factors in the Pathogenesis of MPN

Philadelphia-negative myeloproliferative neoplasms (MPNs) occur when there is over-production of myeloid cells stemming from hematopoietic stem cells with constitutive activation of JAK/STAT signaling, with JAK2(V617F) being the most commonly occurring somatic driver mutation. Chronic inflammation i...

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Detalles Bibliográficos
Autores principales: Ramanathan, Gajalakshmi, Hoover, Brianna M, Fleischman, Angela G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463688/
https://www.ncbi.nlm.nih.gov/pubmed/32722135
http://dx.doi.org/10.3390/cancers12082038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463688/
https://www.ncbi.nlm.nih.gov/pubmed/32722135
http://dx.doi.org/10.3390/cancers12082038

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