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Impact of Host, Lifestyle and Environmental Factors in the Pathogenesis of MPN

Philadelphia-negative myeloproliferative neoplasms (MPNs) occur when there is over-production of myeloid cells stemming from hematopoietic stem cells with constitutive activation of JAK/STAT signaling, with JAK2(V617F) being the most commonly occurring somatic driver mutation. Chronic inflammation i...

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Detalles Bibliográficos
Autores principales:	Ramanathan, Gajalakshmi, Hoover, Brianna M, Fleischman, Angela G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463688/ https://www.ncbi.nlm.nih.gov/pubmed/32722135 http://dx.doi.org/10.3390/cancers12082038

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