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Cyclin E2 Promotes Whole Genome Doubling in Breast Cancer

Genome doubling is an underlying cause of cancer cell aneuploidy and genomic instability, but few drivers have been identified for this process. Due to their physiological roles in the genome reduplication of normal cells, we hypothesised that the oncogenes cyclins E1 and E2 may be drivers of genome...

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Detalles Bibliográficos
Autores principales: Lee, Christine, Fernandez, Kristine J., Alexandrou, Sarah, Sergio, C. Marcelo, Deng, Niantao, Rogers, Samuel, Burgess, Andrew, Caldon, C. Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463708/
https://www.ncbi.nlm.nih.gov/pubmed/32823571
http://dx.doi.org/10.3390/cancers12082268