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Cyclin E2 Promotes Whole Genome Doubling in Breast Cancer
Genome doubling is an underlying cause of cancer cell aneuploidy and genomic instability, but few drivers have been identified for this process. Due to their physiological roles in the genome reduplication of normal cells, we hypothesised that the oncogenes cyclins E1 and E2 may be drivers of genome...
Autores principales: | Lee, Christine, Fernandez, Kristine J., Alexandrou, Sarah, Sergio, C. Marcelo, Deng, Niantao, Rogers, Samuel, Burgess, Andrew, Caldon, C. Elizabeth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463708/ https://www.ncbi.nlm.nih.gov/pubmed/32823571 http://dx.doi.org/10.3390/cancers12082268 |
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