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Co-Chaperones in Targeting and Delivery of Misfolded Proteins to the 26S Proteasome

Protein homeostasis (proteostasis) is essential for the cell and is maintained by a highly conserved protein quality control (PQC) system, which triages newly synthesized, mislocalized and misfolded proteins. The ubiquitin-proteasome system (UPS), molecular chaperones, and co-chaperones are vital PQ...

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Detalles Bibliográficos
Autores principales:	Abildgaard, Amanda B., Gersing, Sarah K., Larsen-Ledet, Sven, Nielsen, Sofie V., Stein, Amelie, Lindorff-Larsen, Kresten, Hartmann-Petersen, Rasmus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463752/ https://www.ncbi.nlm.nih.gov/pubmed/32759676 http://dx.doi.org/10.3390/biom10081141

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