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Polymyxins and Bacterial Membranes: A Review of Antibacterial Activity and Mechanisms of Resistance
Following their initial discovery in the 1940s, polymyxin antibiotics fell into disfavor due to their potential clinical toxicity, especially nephrotoxicity. However, the dry antibiotic development pipeline, together with the rising global prevalence of infections caused by multidrug-resistant (MDR)...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463838/ https://www.ncbi.nlm.nih.gov/pubmed/32784516 http://dx.doi.org/10.3390/membranes10080181 |