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AcrIIA5 Suppresses Base Editors and Reduces Their Off-Target Effects

The CRISPR/nCas9-based cytosine base editors (CBEs) and adenine base editors (ABEs) are capable of catalyzing C•G to T•A or A•T to G•C conversions, respectively, and have become new, powerful tools for achieving precise genetic changes in a wide range of organisms. These base editors hold great prom...

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Detalles Bibliográficos
Autores principales:	Liang, Mingming, Sui, Tingting, Liu, Zhiquan, Chen, Mao, Liu, Hongmei, Shan, Huanhuan, Lai, Liangxue, Li, Zhanjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463901/ https://www.ncbi.nlm.nih.gov/pubmed/32727031 http://dx.doi.org/10.3390/cells9081786

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