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Oxidation of Isodrimeninol with PCC Yields Drimane Derivatives with Activity against Candida Yeast by Inhibition of Lanosterol 14-Alpha Demethylase

Candida species cause an opportunistic yeast infection called Candidiasis, which is responsible for more than 50,000 deaths every year around the world. Effective treatments against candidiasis caused by non-albicans Candida species such as C. glabrata, C. parapsilosis, C. aureus, and C. krusei are...

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Detalles Bibliográficos
Autores principales: Marin, Victor, Iturra, Andres, Opazo, Andres, Schmidt, Bernd, Heydenreich, Matthias, Ortiz, Leandro, Jiménez, Verónica A., Paz, Cristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463952/
https://www.ncbi.nlm.nih.gov/pubmed/32722158
http://dx.doi.org/10.3390/biom10081101