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Enhanced Corneal Penetration of a Poorly Permeable Drug Using Bioadhesive Multiple Microemulsion Technology
Corneal penetration is a key rate limiting step in the bioavailability of topical ophthalmic formulations that incorporate poorly permeable drugs. Recent advances have greatly aided the ocular delivery of such drugs using colloidal drug delivery systems. Ribavirin, a poorly permeable BCS class-III d...
Autores principales: | Ibrahim, Mohamed Moustafa, Maria, Doaa Nabih, Wang, XiangDi, Simpson, Raven N., Hollingsworth, T.J., Jablonski, Monica M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463957/ https://www.ncbi.nlm.nih.gov/pubmed/32722550 http://dx.doi.org/10.3390/pharmaceutics12080704 |
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