Structural Features Defining NF-κB Inhibition by Lignan-Inspired Benzofurans and Benzothiophenes

A series of 2-arylbenzofurans and 2-arylbenzothiophenes was synthesized carrying three different side chains in position five. The synthesized compounds were tested for NF-κB inhibition to establish a structure activity relationship. It was found that both, the side chain in position five and the su...

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Detalles Bibliográficos
Autores principales: Dao-Huy, Toan, Latkolik, Simone, Bräuer, Julia, Pfeil, Andreas, Stuppner, Hermann, Schnürch, Michael, Dirsch, Verena M., Mihovilovic, Marko D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463992/
https://www.ncbi.nlm.nih.gov/pubmed/32751917
http://dx.doi.org/10.3390/biom10081131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463992/
https://www.ncbi.nlm.nih.gov/pubmed/32751917
http://dx.doi.org/10.3390/biom10081131

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