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Structural Features Defining NF-κB Inhibition by Lignan-Inspired Benzofurans and Benzothiophenes
A series of 2-arylbenzofurans and 2-arylbenzothiophenes was synthesized carrying three different side chains in position five. The synthesized compounds were tested for NF-κB inhibition to establish a structure activity relationship. It was found that both, the side chain in position five and the su...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463992/ https://www.ncbi.nlm.nih.gov/pubmed/32751917 http://dx.doi.org/10.3390/biom10081131 |