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Knockdown of Leptin Receptor Affects Macrophage Phenotype in the Tumor Microenvironment Inhibiting Breast Cancer Growth and Progression

Aberrant leptin (Ob) signaling, a hallmark of obesity, has been recognized to influence breast cancer (BC) biology within the tumor microenvironment (TME). Here, we evaluated the impact of leptin receptor (ObR) knockdown in affecting BC phenotype and in mediating the interaction between tumor cells...

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Detalles Bibliográficos
Autores principales:	Gelsomino, Luca, Naimo, Giuseppina Daniela, Malivindi, Rocco, Augimeri, Giuseppina, Panza, Salvatore, Giordano, Cinzia, Barone, Ines, Bonofiglio, Daniela, Mauro, Loredana, Catalano, Stefania, Andò, Sebastiano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464041/ https://www.ncbi.nlm.nih.gov/pubmed/32727138 http://dx.doi.org/10.3390/cancers12082078

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