Cargando…

Discovery of Molecular DNA Methylation-Based Biomarkers through Genome-Wide Analysis of Response Patterns to BCG for Bladder Cancer

Background: Bacillus Calmette-Guérin (BCG) immunotherapy, the standard adjuvant intravesical therapy for some intermediate and most high-risk non-muscle invasive bladder cancers (NMIBCs), suffers from a heterogenous response rate. Molecular markers to help guide responses are scarce and currently no...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ilijazi, Dafina, Pulverer, Walter, Ertl, Iris E., Lemberger, Ursula, Kimura, Shoji, Abufaraj, Mohammad, D’Andrea, David, Pradere, Benjamin, Bruchbacher, Andreas, Graf, Anna, Soria, Francesco, Susani, Martin, Haitel, Andrea, Molinaro, Luca, Pycha, Armin, Comploj, Evi, Pabinger, Stephan, Weinhäusel, Andreas, Egger, Gerda, Shariat, Shahrokh F., Hassler, Melanie R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464079/ https://www.ncbi.nlm.nih.gov/pubmed/32764425 http://dx.doi.org/10.3390/cells9081839

Ejemplares similares

Expression Analysis and Mutational Status of Histone Methyltransferase KMT2D at Different Upper Tract Urothelial Carcinoma Locations
por: Laukhtina, Ekaterina, et al.
Publicado: (2021)

Evaluation of APOBEC3 expression as prognostic marker in squamous cell carcinoma of the penis
por: Trimmel, Bettina, et al.
Publicado: (2022)

Association of super-extended lymphadenectomy at radical cystectomy with perioperative complications and re-hospitalization
por: D’Andrea, David, et al.
Publicado: (2019)

EPIC-TABSAT: analysis tool for targeted bisulfite sequencing experiments and array-based methylation studies
por: Krainer, Julie, et al.
Publicado: (2019)

A systematic review and meta‐analysis of the impact of lymphovascular invasion in bladder cancer transurethral resection specimens
por: Mari, Andrea, et al.
Publicado: (2018)

MSRE-HTPrimer: a high-throughput and genome-wide primer design pipeline optimized for epigenetic research
por: Pandey, Ram Vinay, et al.
Publicado: (2016)

Erratum to: MSRE-HTPrimer: a high-throughput and genome-wide primer design pipeline optimized for epigenetic research
por: Pandey, Ram Vinay, et al.
Publicado: (2016)

MSP-HTPrimer: a high-throughput primer design tool to improve assay design for DNA methylation analysis in epigenetics
por: Pandey, Ram Vinay, et al.
Publicado: (2016)

Systemic therapy for metastatic renal cell carcinoma in the first-line setting: a systematic review and network meta-analysis
por: Mori, Keiichiro, et al.
Publicado: (2020)

Genetic determinants for chemo- and radiotherapy resistance in bladder cancer
por: Mari, Andrea, et al.
Publicado: (2017)

Quantitative Apparent Diffusion Coefficient Measurements Obtained by 3-Tesla MRI Are Correlated with Biomarkers of Bladder Cancer Proliferative Activity
por: Sevcenco, Sabina, et al.
Publicado: (2014)

Multiplexed DNA Methylation Analysis in Colorectal Cancer Using Liquid Biopsy and Its Diagnostic and Predictive Value
por: Pulverer, Walter, et al.
Publicado: (2021)

Unexpected Long Survival in Primary Malignant Melanoma of the Male Urethra
por: Comploj, Evi, et al.
Publicado: (2009)

Prognostic value of testosterone for the castration-resistant prostate cancer patients: a systematic review and meta-analysis
por: Miura, Noriyoshi, et al.
Publicado: (2020)

The Role of (11)C-Choline-PET/CT-Guided Secondary Lymphadenectomy in Patients with PSA Failure after Radical Prostatectomy: Lessons Learned from Eight Cases
por: Martini, Thomas, et al.
Publicado: (2012)

Potential of DNA methylation in rectal cancer as diagnostic and prognostic biomarkers
por: Exner, Ruth, et al.
Publicado: (2015)

Pre-therapy serum albumin-to-globulin ratio in patients treated with neoadjuvant chemotherapy and radical nephroureterectomy for upper tract urothelial carcinoma
por: Pradere, Benjamin, et al.
Publicado: (2020)

Prospective evaluation of the performance of [(68)Ga]Ga-PSMA-11 PET/CT(MRI) for lymph node staging in patients undergoing superextended salvage lymph node dissection after radical prostatectomy
por: Abufaraj, Mohammad, et al.
Publicado: (2019)

Performance of fluoro-2-deoxy-D-glucose positron emission tomography-computed tomography imaging for lymph node staging in bladder and upper tract urothelial carcinoma: a systematic review
por: Aydh, Abdulmajeed, et al.
Publicado: (2020)

MutAid: Sanger and NGS Based Integrated Pipeline for Mutation Identification, Validation and Annotation in Human Molecular Genetics
por: Pandey, Ram Vinay, et al.
Publicado: (2016)

ClinQC: a tool for quality control and cleaning of Sanger and NGS data in clinical research
por: Pandey, Ram Vinay, et al.
Publicado: (2016)

Association of De Ritis ratio with oncological outcomes in patients with non-muscle invasive bladder cancer (NMIBC)
por: Laukhtina, Ekaterina, et al.
Publicado: (2020)

Prognostic role of expression of N-cadherin in patients with upper tract urothelial carcinoma: a multi-institutional study
por: Abufaraj, Mohammad, et al.
Publicado: (2016)

Identification of tumor tissue-derived DNA methylation biomarkers for the detection and therapy response evaluation of metastatic castration resistant prostate cancer in liquid biopsies
por: Dillinger, Thomas, et al.
Publicado: (2022)

Epigenomics of cancer – emerging new concepts
por: Hassler, Melanie R., et al.
Publicado: (2012)

A survey of tools for the analysis of quantitative PCR (qPCR) data
por: Pabinger, Stephan, et al.
Publicado: (2014)

Performance of clinical risk scores and prediction models to identify pathogenic germline variants in patients with advanced prostate cancer
por: Rebhan, Katharina, et al.
Publicado: (2023)

Impact of the Level of Urothelial Carcinoma Involvement of the Prostate on Survival after Radical Cystectomy
por: Moschini, Marco, et al.
Publicado: (2017)

Further Understanding of Urokinase Plasminogen Activator Overexpression in Urothelial Bladder Cancer Progression, Clinical Outcomes and Potential Therapeutic Targets
por: Grossmann, Nico C, et al.
Publicado: (2021)

Prognostic value of the pre-operative serum albumin to globulin ratio in patients with non-metastatic prostate cancer undergoing radical prostatectomy
por: Aydh, Abdulmajeed, et al.
Publicado: (2021)

Associations Between Presenting Symptoms, Clinicopathological Parameters, and Prognosis in a Contemporary Series of Patients With Renal Cell Carcinoma
por: Hofbauer, Sebastian L., et al.
Publicado: (2014)

Intravesical bacillus Calmette-Guérin for bladder cancer: are all the strains equal?
por: D’Andrea, David, et al.
Publicado: (2019)

The significance of De Ritis ratio in patients with radiation-recurrent prostate cancer undergoing salvage radical prostatectomy
por: Quhal, Fahad, et al.
Publicado: (2020)

Prognostic value of the systemic immune-inflammation index in non-muscle invasive bladder cancer
por: Katayama, Satoshi, et al.
Publicado: (2021)

Impact of sex on outcomes after surgery for non-muscle-invasive and muscle-invasive bladder urothelial carcinoma: a systematic review and meta-analysis
por: Mori, Keiichiro, et al.
Publicado: (2022)

Update on systemic treatment of upper tract urothelial carcinoma: a narrative review of the literature
por: Gust, Kilian M., et al.
Publicado: (2021)

Insights into the Pathogenesis of Anaplastic Large-Cell Lymphoma through Genome-wide DNA Methylation Profiling
por: Hassler, Melanie R., et al.
Publicado: (2016)

Methyl-binding domain protein-based DNA isolation from human blood serum combines DNA analyses and serum-autoantibody testing
por: Wielscher, Matthias, et al.
Publicado: (2011)

Apalutamide, enzalutamide, and darolutamide for non-metastatic castration-resistant prostate cancer: a systematic review and network meta-analysis
por: Mori, Keiichiro, et al.
Publicado: (2020)

Blood-Based Biomarkers as Prognostic Factors of Recurrent Disease after Radical Cystectomy: A Systematic Review and Meta-Analysis
por: Ofner, Heidemarie, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_vmkl8b80h2hou3ou5mstk6h78g