Isolation of Two Novel Human Anti-CTLA-4 mAbs with Intriguing Biological Properties on Tumor and NK Cells

The cytotoxic T lymphocyte-antigen 4 (CTLA-4) has been considered an IC exclusively expressed on T cells, where it counteracts the co-stimulatory CD28 receptor, by competing for its binding to CD-80 and CD-86. We recently found that it is expressed also on tumor and NK cells, suggesting other possib...

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Detalles Bibliográficos
Autores principales: Passariello, Margherita, Vetrei, Cinzia, Sasso, Emanuele, Froechlich, Guendalina, Gentile, Chiara, D’Alise, Anna Morena, Zambrano, Nicola, Scarselli, Elisa, Nicosia, Alfredo, De Lorenzo, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464132/
https://www.ncbi.nlm.nih.gov/pubmed/32781690
http://dx.doi.org/10.3390/cancers12082204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464132/
https://www.ncbi.nlm.nih.gov/pubmed/32781690
http://dx.doi.org/10.3390/cancers12082204

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