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Phytochemical Composition and Antimicrobial Activity of Corydalis solida and Pseudofumaria lutea
Corydalis and Pseudofumaria are two closely related genera from the Papaveraceae subfamily Fumarioideae with Corydalis solida (C. solida) and Pseudofumaria lutea (P. lutea) as two representative species. Phytochemical analysis revealed significant differences in the quality and quantity of isoquinol...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464254/ https://www.ncbi.nlm.nih.gov/pubmed/32784618 http://dx.doi.org/10.3390/molecules25163591 |
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author | Zielińska, Sylwia Dziągwa-Becker, Magdalena Piątczak, Ewelina Jezierska-Domaradzka, Anna Brożyna, Malwina Junka, Adam Kucharski, Mariusz Çiçek, Serhat Sezai Zidorn, Christian Matkowski, Adam |
author_facet | Zielińska, Sylwia Dziągwa-Becker, Magdalena Piątczak, Ewelina Jezierska-Domaradzka, Anna Brożyna, Malwina Junka, Adam Kucharski, Mariusz Çiçek, Serhat Sezai Zidorn, Christian Matkowski, Adam |
author_sort | Zielińska, Sylwia |
collection | PubMed |
description | Corydalis and Pseudofumaria are two closely related genera from the Papaveraceae subfamily Fumarioideae with Corydalis solida (C. solida) and Pseudofumaria lutea (P. lutea) as two representative species. Phytochemical analysis revealed significant differences in the quality and quantity of isoquinoline alkaloids, phenolic compounds and non-phenolic carboxylic acids between aerial and underground parts of both species. Using the Liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS) technique, 21 compounds were identified: five protoberberine derivatives, three protopine derivatives, four phenanthridine derivatives, as well as three carboxylic acids, two hydroxycinnamic acids, one chlorogenic acid, one phenolic aldehyde, and two flavonoids. Moroever, significant differences in the content of individual compounds were observed between the two studied species. The phytochemical profile of C. solida showed a higher variety of compounds that were present in lower amounts, whereas P. lutea extracts contained fewer compounds but in larger quantities. Protopine was one of the most abundant constituents in C. solida (440–1125 µg/g d.w.) and in P. lutea (1036–1934 µg/g d.w.). Moreover, considerable amounts of coptisine (1526 µg/g) and quercetin (3247 µg/g) were detected in the aerial parts of P. lutea. Extracts from aerial and underground parts of both species were also examined for the antimicrobial potential against S. aureus, P. aeruginosa and C. albicans. P. lutea herb extract was the most effective (MIC at 0.39 mg/L) against all three pathogens. |
format | Online Article Text |
id | pubmed-7464254 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-74642542020-09-04 Phytochemical Composition and Antimicrobial Activity of Corydalis solida and Pseudofumaria lutea Zielińska, Sylwia Dziągwa-Becker, Magdalena Piątczak, Ewelina Jezierska-Domaradzka, Anna Brożyna, Malwina Junka, Adam Kucharski, Mariusz Çiçek, Serhat Sezai Zidorn, Christian Matkowski, Adam Molecules Article Corydalis and Pseudofumaria are two closely related genera from the Papaveraceae subfamily Fumarioideae with Corydalis solida (C. solida) and Pseudofumaria lutea (P. lutea) as two representative species. Phytochemical analysis revealed significant differences in the quality and quantity of isoquinoline alkaloids, phenolic compounds and non-phenolic carboxylic acids between aerial and underground parts of both species. Using the Liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS) technique, 21 compounds were identified: five protoberberine derivatives, three protopine derivatives, four phenanthridine derivatives, as well as three carboxylic acids, two hydroxycinnamic acids, one chlorogenic acid, one phenolic aldehyde, and two flavonoids. Moroever, significant differences in the content of individual compounds were observed between the two studied species. The phytochemical profile of C. solida showed a higher variety of compounds that were present in lower amounts, whereas P. lutea extracts contained fewer compounds but in larger quantities. Protopine was one of the most abundant constituents in C. solida (440–1125 µg/g d.w.) and in P. lutea (1036–1934 µg/g d.w.). Moreover, considerable amounts of coptisine (1526 µg/g) and quercetin (3247 µg/g) were detected in the aerial parts of P. lutea. Extracts from aerial and underground parts of both species were also examined for the antimicrobial potential against S. aureus, P. aeruginosa and C. albicans. P. lutea herb extract was the most effective (MIC at 0.39 mg/L) against all three pathogens. MDPI 2020-08-07 /pmc/articles/PMC7464254/ /pubmed/32784618 http://dx.doi.org/10.3390/molecules25163591 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Zielińska, Sylwia Dziągwa-Becker, Magdalena Piątczak, Ewelina Jezierska-Domaradzka, Anna Brożyna, Malwina Junka, Adam Kucharski, Mariusz Çiçek, Serhat Sezai Zidorn, Christian Matkowski, Adam Phytochemical Composition and Antimicrobial Activity of Corydalis solida and Pseudofumaria lutea |
title | Phytochemical Composition and Antimicrobial Activity of Corydalis solida and Pseudofumaria lutea |
title_full | Phytochemical Composition and Antimicrobial Activity of Corydalis solida and Pseudofumaria lutea |
title_fullStr | Phytochemical Composition and Antimicrobial Activity of Corydalis solida and Pseudofumaria lutea |
title_full_unstemmed | Phytochemical Composition and Antimicrobial Activity of Corydalis solida and Pseudofumaria lutea |
title_short | Phytochemical Composition and Antimicrobial Activity of Corydalis solida and Pseudofumaria lutea |
title_sort | phytochemical composition and antimicrobial activity of corydalis solida and pseudofumaria lutea |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464254/ https://www.ncbi.nlm.nih.gov/pubmed/32784618 http://dx.doi.org/10.3390/molecules25163591 |
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