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Delayed Ischemic Neurological Deficit after Uneventful Elective Clipping of Unruptured Intracranial Aneurysms

Cerebral vasospasm and subsequent delayed ischemic neurological deficit is a typical sequela of acute subarachnoid hemorrhage after aneurysm rupture. The occurrence of vasospasms after uncomplicated surgery of an unruptured aneurysm without history of suspected rupture is extremely rare. The pathoge...

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Autores principales: Vachata, Petr, Lodin, Jan, Hejčl, Aleš, Cihlář, Filip, Sameš, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464283/
https://www.ncbi.nlm.nih.gov/pubmed/32751242
http://dx.doi.org/10.3390/brainsci10080495
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author Vachata, Petr
Lodin, Jan
Hejčl, Aleš
Cihlář, Filip
Sameš, Martin
author_facet Vachata, Petr
Lodin, Jan
Hejčl, Aleš
Cihlář, Filip
Sameš, Martin
author_sort Vachata, Petr
collection PubMed
description Cerebral vasospasm and subsequent delayed ischemic neurological deficit is a typical sequela of acute subarachnoid hemorrhage after aneurysm rupture. The occurrence of vasospasms after uncomplicated surgery of an unruptured aneurysm without history of suspected rupture is extremely rare. The pathogenesis and severity of cerebral vasospasms is typically correlated with the amount of blood breakdown products extravasated during subarachnoid hemorrhage. In rare cases, where vasospasms occur after unruptured aneurysm surgery, the pathogenesis is most likely multifactorial and unclear. We present two cases of vasospasms following uncomplicated clipping of middle cerebral artery (MCA) aneurysms and a review of literature. Early diagnosis and therapy of this rare complication are necessary to achieve optimal clinical outcomes.
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spelling pubmed-74642832020-09-04 Delayed Ischemic Neurological Deficit after Uneventful Elective Clipping of Unruptured Intracranial Aneurysms Vachata, Petr Lodin, Jan Hejčl, Aleš Cihlář, Filip Sameš, Martin Brain Sci Case Report Cerebral vasospasm and subsequent delayed ischemic neurological deficit is a typical sequela of acute subarachnoid hemorrhage after aneurysm rupture. The occurrence of vasospasms after uncomplicated surgery of an unruptured aneurysm without history of suspected rupture is extremely rare. The pathogenesis and severity of cerebral vasospasms is typically correlated with the amount of blood breakdown products extravasated during subarachnoid hemorrhage. In rare cases, where vasospasms occur after unruptured aneurysm surgery, the pathogenesis is most likely multifactorial and unclear. We present two cases of vasospasms following uncomplicated clipping of middle cerebral artery (MCA) aneurysms and a review of literature. Early diagnosis and therapy of this rare complication are necessary to achieve optimal clinical outcomes. MDPI 2020-07-29 /pmc/articles/PMC7464283/ /pubmed/32751242 http://dx.doi.org/10.3390/brainsci10080495 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Vachata, Petr
Lodin, Jan
Hejčl, Aleš
Cihlář, Filip
Sameš, Martin
Delayed Ischemic Neurological Deficit after Uneventful Elective Clipping of Unruptured Intracranial Aneurysms
title Delayed Ischemic Neurological Deficit after Uneventful Elective Clipping of Unruptured Intracranial Aneurysms
title_full Delayed Ischemic Neurological Deficit after Uneventful Elective Clipping of Unruptured Intracranial Aneurysms
title_fullStr Delayed Ischemic Neurological Deficit after Uneventful Elective Clipping of Unruptured Intracranial Aneurysms
title_full_unstemmed Delayed Ischemic Neurological Deficit after Uneventful Elective Clipping of Unruptured Intracranial Aneurysms
title_short Delayed Ischemic Neurological Deficit after Uneventful Elective Clipping of Unruptured Intracranial Aneurysms
title_sort delayed ischemic neurological deficit after uneventful elective clipping of unruptured intracranial aneurysms
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464283/
https://www.ncbi.nlm.nih.gov/pubmed/32751242
http://dx.doi.org/10.3390/brainsci10080495
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