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Novel Histone-Based DNA Carrier Targeting Cancer-Associated Fibroblasts
Nuclear proteins, like histone H2A, are promising non-viral carriers for gene delivery since they are biocompatible, biodegradable, bear intrinsic nuclear localization signal, and are easy to modify. The addition of surface-protein-binding ligand to histone H2A may increase its DNA delivery efficien...
Autores principales: | Kuzmich, Alexey, Rakitina, Olga, Didych, Dmitry, Potapov, Victor, Zinovyeva, Marina, Alekseenko, Irina, Sverdlov, Eugene |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464289/ https://www.ncbi.nlm.nih.gov/pubmed/32751200 http://dx.doi.org/10.3390/polym12081695 |
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