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Effect of Aerobic and Anaerobic Exercise on the Complement System of Proteins in Healthy Young Males

This study was aimed at examining the impact of common types of physical efforts used to determine the aerobic and anaerobic performance of the participants on the complement system in their peripheral blood. Fifty-one physically active young males aged 16 years old (range 15–21 years) were divided...

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Autores principales: Kostrzewa-Nowak, Dorota, Kubaszewska, Joanna, Nowakowska, Anna, Nowak, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464301/
https://www.ncbi.nlm.nih.gov/pubmed/32717972
http://dx.doi.org/10.3390/jcm9082357
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author Kostrzewa-Nowak, Dorota
Kubaszewska, Joanna
Nowakowska, Anna
Nowak, Robert
author_facet Kostrzewa-Nowak, Dorota
Kubaszewska, Joanna
Nowakowska, Anna
Nowak, Robert
author_sort Kostrzewa-Nowak, Dorota
collection PubMed
description This study was aimed at examining the impact of common types of physical efforts used to determine the aerobic and anaerobic performance of the participants on the complement system in their peripheral blood. Fifty-one physically active young males aged 16 years old (range 15–21 years) were divided into two age groups (younger, 15–17 years old and older, 18–21 years old) and performed two types of intensive efforts: aerobic (endurance; 20-m shuttle run test; Beep) and anaerobic (speed; repeated speed ability test; RSA). Venous blood samples were collected before and after each exercise (5 and 60 min) to profile the complement system components, namely the levels of C2, C3, C3a, iC3b, and C4. The endurance effort caused a decrease in the post-test C3 (p < 0.001 for both age groups) and increase in post-test C3a (p < 0.001 and p < 0.01 for the younger and older group, respectively), recovery iC3b (p < 0.001 and p < 0.05 for younger and older group, respectively), recovery C2 (p < 0.01 for both age groups), and post-test C4 (p < 0.05 and p < 0.01 for the younger and older group, respectively) levels, while the speed effort caused a decrease only in the post-test C2 (p < 0.05 for younger participants) and post-test C4 levels (p < 0.001 and p < 0.01 for the younger and older group, respectively) and an increase in the recovery C3a level (p < 0.05). Our study provides evidence that different types of physical effort promote different immune responses in physically active young men. Aerobic exercise induced the activation of an alternative pathway of the complement system, whilst the anaerobic effort had little influence. A better understanding of the post-exercise immune response provides a framework to prescribe physical activity to achieve different health outcomes.
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spelling pubmed-74643012020-09-04 Effect of Aerobic and Anaerobic Exercise on the Complement System of Proteins in Healthy Young Males Kostrzewa-Nowak, Dorota Kubaszewska, Joanna Nowakowska, Anna Nowak, Robert J Clin Med Article This study was aimed at examining the impact of common types of physical efforts used to determine the aerobic and anaerobic performance of the participants on the complement system in their peripheral blood. Fifty-one physically active young males aged 16 years old (range 15–21 years) were divided into two age groups (younger, 15–17 years old and older, 18–21 years old) and performed two types of intensive efforts: aerobic (endurance; 20-m shuttle run test; Beep) and anaerobic (speed; repeated speed ability test; RSA). Venous blood samples were collected before and after each exercise (5 and 60 min) to profile the complement system components, namely the levels of C2, C3, C3a, iC3b, and C4. The endurance effort caused a decrease in the post-test C3 (p < 0.001 for both age groups) and increase in post-test C3a (p < 0.001 and p < 0.01 for the younger and older group, respectively), recovery iC3b (p < 0.001 and p < 0.05 for younger and older group, respectively), recovery C2 (p < 0.01 for both age groups), and post-test C4 (p < 0.05 and p < 0.01 for the younger and older group, respectively) levels, while the speed effort caused a decrease only in the post-test C2 (p < 0.05 for younger participants) and post-test C4 levels (p < 0.001 and p < 0.01 for the younger and older group, respectively) and an increase in the recovery C3a level (p < 0.05). Our study provides evidence that different types of physical effort promote different immune responses in physically active young men. Aerobic exercise induced the activation of an alternative pathway of the complement system, whilst the anaerobic effort had little influence. A better understanding of the post-exercise immune response provides a framework to prescribe physical activity to achieve different health outcomes. MDPI 2020-07-23 /pmc/articles/PMC7464301/ /pubmed/32717972 http://dx.doi.org/10.3390/jcm9082357 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kostrzewa-Nowak, Dorota
Kubaszewska, Joanna
Nowakowska, Anna
Nowak, Robert
Effect of Aerobic and Anaerobic Exercise on the Complement System of Proteins in Healthy Young Males
title Effect of Aerobic and Anaerobic Exercise on the Complement System of Proteins in Healthy Young Males
title_full Effect of Aerobic and Anaerobic Exercise on the Complement System of Proteins in Healthy Young Males
title_fullStr Effect of Aerobic and Anaerobic Exercise on the Complement System of Proteins in Healthy Young Males
title_full_unstemmed Effect of Aerobic and Anaerobic Exercise on the Complement System of Proteins in Healthy Young Males
title_short Effect of Aerobic and Anaerobic Exercise on the Complement System of Proteins in Healthy Young Males
title_sort effect of aerobic and anaerobic exercise on the complement system of proteins in healthy young males
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464301/
https://www.ncbi.nlm.nih.gov/pubmed/32717972
http://dx.doi.org/10.3390/jcm9082357
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