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Transport Oligonucleotides—A Novel System for Intracellular Delivery of Antisense Therapeutics
Biological activity of antisense oligonucleotides (asON), especially those with a neutral backbone, is often attenuated by poor cellular accumulation. In the present proof-of-concept study, we propose a novel delivery system for asONs which implies the delivery of modified antisense oligonucleotides...
Autores principales: | Markov, Oleg V., Filatov, Anton V., Kupryushkin, Maxim S., Chernikov, Ivan V., Patutina, Olga A., Strunov, Anton A., Chernolovskaya, Elena L., Vlassov, Valentin V., Pyshnyi, Dmitrii V., Zenkova, Marina A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464317/ https://www.ncbi.nlm.nih.gov/pubmed/32796768 http://dx.doi.org/10.3390/molecules25163663 |
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