Cargando…
Ducrosia spp., Rare Plants with Promising Phytochemical and Pharmacological Characteristics: An Updated Review
The rare genus Ducrosia (Apiaceae family) consists of six species, which are mainly native to Asia, specifically to Iran and Iraq. The aerial parts of D. anethifolia, as the most common species, have been traditionally consumed to relieve headache, backache and colic pain, and have also been used as...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464381/ https://www.ncbi.nlm.nih.gov/pubmed/32752066 http://dx.doi.org/10.3390/ph13080175 |
_version_ | 1783577351814119424 |
---|---|
author | Mottaghipisheh, Javad Boveiri Dehsheikh, Anahita Mahmoodi Sourestani, Mohammad Kiss, Tivadar Hohmann, Judit Csupor, Dezső |
author_facet | Mottaghipisheh, Javad Boveiri Dehsheikh, Anahita Mahmoodi Sourestani, Mohammad Kiss, Tivadar Hohmann, Judit Csupor, Dezső |
author_sort | Mottaghipisheh, Javad |
collection | PubMed |
description | The rare genus Ducrosia (Apiaceae family) consists of six species, which are mainly native to Asia, specifically to Iran and Iraq. The aerial parts of D. anethifolia, as the most common species, have been traditionally consumed to relieve headache, backache and colic pain, and have also been used as an anxiolytic, an antidepressant, and for treating insomnia. The antispasmodic and carminative effects of D. assadii, and the analgesic activity of D. flabellifolia, along with the insecticidal activities and use as a remedy of skin infections of D. ismaelis, have been previously documented. Among the 49 non-volatile secondary metabolites identified from D. anethifolia and D. ismaelis, 17 linear furanocoumarins and 8 flavonoids have been characterized. The essential oil compositions of four species, including D. anethifolia, D. assadii, D. flabellifolia and D. ismaelis, have been analyzed, whereby aldehyde hydrocarbons, including decanal (10.1–74.0%) and dodecanal (7.2–33.41%), and α-pinene (4.0–70.3%), were identified as the main aroma constituents. From the species of the genus, the bioactivities of D. anethifolia, as well as D. ismaelis, D. assadii and D. flabellifolia, have been previously investigated. Except one clinical trial, all the pharmacological data are derived from preclinical tests, predominantly focusing on antimicrobial, antioxidant, antiproliferative and cytotoxic activities in vitro, and neuroprotective, antidiabetic and analgesic effects in vivo. Considering the vast ethnobotanical uses of the plants in Iranian folk medicine, the phytochemical and pharmacological analysis of un-investigated species might be promising. Furthermore, due to extensive consumption of the Ducrosia genus, more scientific data are needed to support the safety and efficacy of these plants. |
format | Online Article Text |
id | pubmed-7464381 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-74643812020-09-04 Ducrosia spp., Rare Plants with Promising Phytochemical and Pharmacological Characteristics: An Updated Review Mottaghipisheh, Javad Boveiri Dehsheikh, Anahita Mahmoodi Sourestani, Mohammad Kiss, Tivadar Hohmann, Judit Csupor, Dezső Pharmaceuticals (Basel) Review The rare genus Ducrosia (Apiaceae family) consists of six species, which are mainly native to Asia, specifically to Iran and Iraq. The aerial parts of D. anethifolia, as the most common species, have been traditionally consumed to relieve headache, backache and colic pain, and have also been used as an anxiolytic, an antidepressant, and for treating insomnia. The antispasmodic and carminative effects of D. assadii, and the analgesic activity of D. flabellifolia, along with the insecticidal activities and use as a remedy of skin infections of D. ismaelis, have been previously documented. Among the 49 non-volatile secondary metabolites identified from D. anethifolia and D. ismaelis, 17 linear furanocoumarins and 8 flavonoids have been characterized. The essential oil compositions of four species, including D. anethifolia, D. assadii, D. flabellifolia and D. ismaelis, have been analyzed, whereby aldehyde hydrocarbons, including decanal (10.1–74.0%) and dodecanal (7.2–33.41%), and α-pinene (4.0–70.3%), were identified as the main aroma constituents. From the species of the genus, the bioactivities of D. anethifolia, as well as D. ismaelis, D. assadii and D. flabellifolia, have been previously investigated. Except one clinical trial, all the pharmacological data are derived from preclinical tests, predominantly focusing on antimicrobial, antioxidant, antiproliferative and cytotoxic activities in vitro, and neuroprotective, antidiabetic and analgesic effects in vivo. Considering the vast ethnobotanical uses of the plants in Iranian folk medicine, the phytochemical and pharmacological analysis of un-investigated species might be promising. Furthermore, due to extensive consumption of the Ducrosia genus, more scientific data are needed to support the safety and efficacy of these plants. MDPI 2020-07-31 /pmc/articles/PMC7464381/ /pubmed/32752066 http://dx.doi.org/10.3390/ph13080175 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Mottaghipisheh, Javad Boveiri Dehsheikh, Anahita Mahmoodi Sourestani, Mohammad Kiss, Tivadar Hohmann, Judit Csupor, Dezső Ducrosia spp., Rare Plants with Promising Phytochemical and Pharmacological Characteristics: An Updated Review |
title | Ducrosia spp., Rare Plants with Promising Phytochemical and Pharmacological Characteristics: An Updated Review |
title_full | Ducrosia spp., Rare Plants with Promising Phytochemical and Pharmacological Characteristics: An Updated Review |
title_fullStr | Ducrosia spp., Rare Plants with Promising Phytochemical and Pharmacological Characteristics: An Updated Review |
title_full_unstemmed | Ducrosia spp., Rare Plants with Promising Phytochemical and Pharmacological Characteristics: An Updated Review |
title_short | Ducrosia spp., Rare Plants with Promising Phytochemical and Pharmacological Characteristics: An Updated Review |
title_sort | ducrosia spp., rare plants with promising phytochemical and pharmacological characteristics: an updated review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464381/ https://www.ncbi.nlm.nih.gov/pubmed/32752066 http://dx.doi.org/10.3390/ph13080175 |
work_keys_str_mv | AT mottaghipishehjavad ducrosiaspprareplantswithpromisingphytochemicalandpharmacologicalcharacteristicsanupdatedreview AT boveiridehsheikhanahita ducrosiaspprareplantswithpromisingphytochemicalandpharmacologicalcharacteristicsanupdatedreview AT mahmoodisourestanimohammad ducrosiaspprareplantswithpromisingphytochemicalandpharmacologicalcharacteristicsanupdatedreview AT kisstivadar ducrosiaspprareplantswithpromisingphytochemicalandpharmacologicalcharacteristicsanupdatedreview AT hohmannjudit ducrosiaspprareplantswithpromisingphytochemicalandpharmacologicalcharacteristicsanupdatedreview AT csupordezso ducrosiaspprareplantswithpromisingphytochemicalandpharmacologicalcharacteristicsanupdatedreview |