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Ducrosia spp., Rare Plants with Promising Phytochemical and Pharmacological Characteristics: An Updated Review

The rare genus Ducrosia (Apiaceae family) consists of six species, which are mainly native to Asia, specifically to Iran and Iraq. The aerial parts of D. anethifolia, as the most common species, have been traditionally consumed to relieve headache, backache and colic pain, and have also been used as...

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Autores principales: Mottaghipisheh, Javad, Boveiri Dehsheikh, Anahita, Mahmoodi Sourestani, Mohammad, Kiss, Tivadar, Hohmann, Judit, Csupor, Dezső
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464381/
https://www.ncbi.nlm.nih.gov/pubmed/32752066
http://dx.doi.org/10.3390/ph13080175
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author Mottaghipisheh, Javad
Boveiri Dehsheikh, Anahita
Mahmoodi Sourestani, Mohammad
Kiss, Tivadar
Hohmann, Judit
Csupor, Dezső
author_facet Mottaghipisheh, Javad
Boveiri Dehsheikh, Anahita
Mahmoodi Sourestani, Mohammad
Kiss, Tivadar
Hohmann, Judit
Csupor, Dezső
author_sort Mottaghipisheh, Javad
collection PubMed
description The rare genus Ducrosia (Apiaceae family) consists of six species, which are mainly native to Asia, specifically to Iran and Iraq. The aerial parts of D. anethifolia, as the most common species, have been traditionally consumed to relieve headache, backache and colic pain, and have also been used as an anxiolytic, an antidepressant, and for treating insomnia. The antispasmodic and carminative effects of D. assadii, and the analgesic activity of D. flabellifolia, along with the insecticidal activities and use as a remedy of skin infections of D. ismaelis, have been previously documented. Among the 49 non-volatile secondary metabolites identified from D. anethifolia and D. ismaelis, 17 linear furanocoumarins and 8 flavonoids have been characterized. The essential oil compositions of four species, including D. anethifolia, D. assadii, D. flabellifolia and D. ismaelis, have been analyzed, whereby aldehyde hydrocarbons, including decanal (10.1–74.0%) and dodecanal (7.2–33.41%), and α-pinene (4.0–70.3%), were identified as the main aroma constituents. From the species of the genus, the bioactivities of D. anethifolia, as well as D. ismaelis, D. assadii and D. flabellifolia, have been previously investigated. Except one clinical trial, all the pharmacological data are derived from preclinical tests, predominantly focusing on antimicrobial, antioxidant, antiproliferative and cytotoxic activities in vitro, and neuroprotective, antidiabetic and analgesic effects in vivo. Considering the vast ethnobotanical uses of the plants in Iranian folk medicine, the phytochemical and pharmacological analysis of un-investigated species might be promising. Furthermore, due to extensive consumption of the Ducrosia genus, more scientific data are needed to support the safety and efficacy of these plants.
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spelling pubmed-74643812020-09-04 Ducrosia spp., Rare Plants with Promising Phytochemical and Pharmacological Characteristics: An Updated Review Mottaghipisheh, Javad Boveiri Dehsheikh, Anahita Mahmoodi Sourestani, Mohammad Kiss, Tivadar Hohmann, Judit Csupor, Dezső Pharmaceuticals (Basel) Review The rare genus Ducrosia (Apiaceae family) consists of six species, which are mainly native to Asia, specifically to Iran and Iraq. The aerial parts of D. anethifolia, as the most common species, have been traditionally consumed to relieve headache, backache and colic pain, and have also been used as an anxiolytic, an antidepressant, and for treating insomnia. The antispasmodic and carminative effects of D. assadii, and the analgesic activity of D. flabellifolia, along with the insecticidal activities and use as a remedy of skin infections of D. ismaelis, have been previously documented. Among the 49 non-volatile secondary metabolites identified from D. anethifolia and D. ismaelis, 17 linear furanocoumarins and 8 flavonoids have been characterized. The essential oil compositions of four species, including D. anethifolia, D. assadii, D. flabellifolia and D. ismaelis, have been analyzed, whereby aldehyde hydrocarbons, including decanal (10.1–74.0%) and dodecanal (7.2–33.41%), and α-pinene (4.0–70.3%), were identified as the main aroma constituents. From the species of the genus, the bioactivities of D. anethifolia, as well as D. ismaelis, D. assadii and D. flabellifolia, have been previously investigated. Except one clinical trial, all the pharmacological data are derived from preclinical tests, predominantly focusing on antimicrobial, antioxidant, antiproliferative and cytotoxic activities in vitro, and neuroprotective, antidiabetic and analgesic effects in vivo. Considering the vast ethnobotanical uses of the plants in Iranian folk medicine, the phytochemical and pharmacological analysis of un-investigated species might be promising. Furthermore, due to extensive consumption of the Ducrosia genus, more scientific data are needed to support the safety and efficacy of these plants. MDPI 2020-07-31 /pmc/articles/PMC7464381/ /pubmed/32752066 http://dx.doi.org/10.3390/ph13080175 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Mottaghipisheh, Javad
Boveiri Dehsheikh, Anahita
Mahmoodi Sourestani, Mohammad
Kiss, Tivadar
Hohmann, Judit
Csupor, Dezső
Ducrosia spp., Rare Plants with Promising Phytochemical and Pharmacological Characteristics: An Updated Review
title Ducrosia spp., Rare Plants with Promising Phytochemical and Pharmacological Characteristics: An Updated Review
title_full Ducrosia spp., Rare Plants with Promising Phytochemical and Pharmacological Characteristics: An Updated Review
title_fullStr Ducrosia spp., Rare Plants with Promising Phytochemical and Pharmacological Characteristics: An Updated Review
title_full_unstemmed Ducrosia spp., Rare Plants with Promising Phytochemical and Pharmacological Characteristics: An Updated Review
title_short Ducrosia spp., Rare Plants with Promising Phytochemical and Pharmacological Characteristics: An Updated Review
title_sort ducrosia spp., rare plants with promising phytochemical and pharmacological characteristics: an updated review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464381/
https://www.ncbi.nlm.nih.gov/pubmed/32752066
http://dx.doi.org/10.3390/ph13080175
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