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Super-Resolution Microscopy Reveals an Altered Fibrin Network in Cirrhosis: The Key Role of Oxidative Stress in Fibrinogen Structural Modifications

Cirrhotic patients show a reduced synthesis of both pro- and anti-coagulant factors. Recent reports indicate that they are characterized by a higher risk of thrombotic rather than hemorrhagic complications, but the mechanisms conferring this risk are not fully elucidated. Oxidative-mediated fibrinog...

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Detalles Bibliográficos
Autores principales: Becatti, Matteo, Mannucci, Amanda, Argento, Flavia Rita, Gitto, Stefano, Vizzutti, Francesco, Marra, Fabio, Taddei, Niccolò, Fiorillo, Claudia, Laffi, Giacomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464401/
https://www.ncbi.nlm.nih.gov/pubmed/32806658
http://dx.doi.org/10.3390/antiox9080737