Cargando…
Syk Kinase Inhibitors Synergize with Artemisinins by Enhancing Oxidative Stress in Plasmodium falciparum-Parasitized Erythrocytes
Although artemisinin-based combination therapies (ACTs) treat Plasmodium falciparum malaria effectively throughout most of the world, the recent expansion of ACT-resistant strains in some countries of the Greater Mekong Subregion (GMS) further increased the interest in improving the effectiveness of...
Autores principales: | Tsamesidis, Ioannis, Reybier, Karine, Marchetti, Giuseppe, Pau, Maria Carmina, Virdis, Patrizia, Fozza, Claudio, Nepveu, Francoise, Low, Philip S., Turrini, Francesco Michelangelo, Pantaleo, Antonella |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464437/ https://www.ncbi.nlm.nih.gov/pubmed/32824055 http://dx.doi.org/10.3390/antiox9080753 |
Ejemplares similares
-
Syk Inhibitors: New Computational Insights into Their Intraerythrocytic Action in Plasmodium falciparum Malaria
por: Marchetti, Giuseppe, et al.
Publicado: (2020) -
Oxidation of Erythrocytes Enhance the Production of Reactive Species in the Presence of Artemisinins
por: Tsamesidis, Ioannis, et al.
Publicado: (2020) -
Induction of high tolerance to artemisinin by sub-lethal administration: A new in vitro model of P. falciparum
por: De Lucia, Serena, et al.
Publicado: (2018) -
In Vitro and In Silico Antimalarial Evaluation of FM-AZ, a New Artemisinin Derivative
por: Tsamesidis, Ioannis, et al.
Publicado: (2022) -
Band 3 Erythrocyte Membrane Protein Acts as Redox Stress Sensor Leading to Its Phosphorylation by p(72) Syk
por: Pantaleo, Antonella, et al.
Publicado: (2016)