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Anthrax Toxin Detection: From In Vivo Studies to Diagnostic Applications
Anthrax toxins are produced by Bacillus anthracis throughout infection and shape the physiopathogenesis of the disease. They are produced in low quantities but are highly efficient. They have thus been long ignored, but recent biochemical methods have improved our knowledge in animal models. This ar...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464488/ https://www.ncbi.nlm.nih.gov/pubmed/32717946 http://dx.doi.org/10.3390/microorganisms8081103 |
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author | Tournier, Jean-Nicolas Rougeaux, Clémence |
author_facet | Tournier, Jean-Nicolas Rougeaux, Clémence |
author_sort | Tournier, Jean-Nicolas |
collection | PubMed |
description | Anthrax toxins are produced by Bacillus anthracis throughout infection and shape the physiopathogenesis of the disease. They are produced in low quantities but are highly efficient. They have thus been long ignored, but recent biochemical methods have improved our knowledge in animal models. This article reviews the various methods that have been used and how they could be applied to clinical diagnosis. |
format | Online Article Text |
id | pubmed-7464488 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-74644882020-09-04 Anthrax Toxin Detection: From In Vivo Studies to Diagnostic Applications Tournier, Jean-Nicolas Rougeaux, Clémence Microorganisms Review Anthrax toxins are produced by Bacillus anthracis throughout infection and shape the physiopathogenesis of the disease. They are produced in low quantities but are highly efficient. They have thus been long ignored, but recent biochemical methods have improved our knowledge in animal models. This article reviews the various methods that have been used and how they could be applied to clinical diagnosis. MDPI 2020-07-23 /pmc/articles/PMC7464488/ /pubmed/32717946 http://dx.doi.org/10.3390/microorganisms8081103 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Tournier, Jean-Nicolas Rougeaux, Clémence Anthrax Toxin Detection: From In Vivo Studies to Diagnostic Applications |
title | Anthrax Toxin Detection: From In Vivo Studies to Diagnostic Applications |
title_full | Anthrax Toxin Detection: From In Vivo Studies to Diagnostic Applications |
title_fullStr | Anthrax Toxin Detection: From In Vivo Studies to Diagnostic Applications |
title_full_unstemmed | Anthrax Toxin Detection: From In Vivo Studies to Diagnostic Applications |
title_short | Anthrax Toxin Detection: From In Vivo Studies to Diagnostic Applications |
title_sort | anthrax toxin detection: from in vivo studies to diagnostic applications |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464488/ https://www.ncbi.nlm.nih.gov/pubmed/32717946 http://dx.doi.org/10.3390/microorganisms8081103 |
work_keys_str_mv | AT tournierjeannicolas anthraxtoxindetectionfrominvivostudiestodiagnosticapplications AT rougeauxclemence anthraxtoxindetectionfrominvivostudiestodiagnosticapplications |